Long-Term Effects of Perinatal Glucocorticoid Treatment on the Heart

Willem B. de Vries; Matthijs F.M. van Oosterhout; Miriam P. Bal; Jan Baan; Cobi J. Heijnen; Frank van Bel

doi:10.2174/157339607781369564

Abstract

Chronic lung disease in the extremely preterm baby is still a major complication in neonatal intensive care. Perinatal (ante- and neonatal) glucocorticoids are widely used to prevent severe infant respiratory distress syndrome and/or to reduce chronic lung disease respectively. A review of the literature regarding the cardiovascular side effects of antenatal and neonatal glucocorticoids is presented here.

Keywords: chronic lung disease, betamethasone, hypertrophy, protein/DNA ratio, Respiratory Distress Syndrome

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