Insulin and the Blood-Brain Barrier

Title: Insulin and the Blood-Brain Barrier

Volume: 9 Issue: 10

Author(s): Stephen C. Woods, Randy J. Seeley, Denis G. Baskin and Michael W. Schwartz

Affiliation:

Keywords: Insulin, Blood-Brain Barrier, homeostasis

Abstract: Although several possible mechanisms exist by which the pancreatic hormone, insulin, could enter the brain from the blood, most evidence suggests that the majority of it enters primarily by a receptor-mediated transport process. Many factors influence the rate of entry, including fasting and refeeding and several pathological conditions. Within the brain insulin acts on specific receptors to influence a number of behaviors, and especially caloric homeostasis and cognition.

Cite this article as:

Woods C. Stephen, Seeley J. Randy, Baskin G. Denis and Schwartz W. Michael, Insulin and the Blood-Brain Barrier, Current Pharmaceutical Design 2003; 9 (10) . https://dx.doi.org/10.2174/1381612033455323