Abstract
Tuberculosis is a major public health concern. The present article reviews the current updates on the usage of nanoparticles against tuberculosis and recent patents that could develop into novel therapeutics available to the clinical armamentarium for the TB management. The drug delivery systems involving nanoparticles are suitable against chronic diseases such as tuberculosis. Polymers in many forms like liposomes, dendrimers, Nanoemulsions can be used as synthetic and natural carriers for first line and second line drugs employed for chemotherapy. Not only are the drugs sustainably released in organs and plasma, but also their dosages as well as adverse effects have been reduced, the drug interaction has increased and the drug resistant bacteria have been targeted. The hurdles in the development of anti-tuberculosis have made Nano medicines to act as a silver lining.
Keywords: Dendrimers, liposomes, Mycobacterium, nano medicine, nanoparticles, tuberculosis.
Recent Patents on Inflammation & Allergy Drug Discovery
Title:Formulation of Nanoparticles Against TB - A Review
Volume: 9 Issue: 2
Author(s): Mandeep Kataria, Manisha Sethi, Jagjit Kaur, Sandeep Punia and Kuldeep Kumar
Affiliation:
Keywords: Dendrimers, liposomes, Mycobacterium, nano medicine, nanoparticles, tuberculosis.
Abstract: Tuberculosis is a major public health concern. The present article reviews the current updates on the usage of nanoparticles against tuberculosis and recent patents that could develop into novel therapeutics available to the clinical armamentarium for the TB management. The drug delivery systems involving nanoparticles are suitable against chronic diseases such as tuberculosis. Polymers in many forms like liposomes, dendrimers, Nanoemulsions can be used as synthetic and natural carriers for first line and second line drugs employed for chemotherapy. Not only are the drugs sustainably released in organs and plasma, but also their dosages as well as adverse effects have been reduced, the drug interaction has increased and the drug resistant bacteria have been targeted. The hurdles in the development of anti-tuberculosis have made Nano medicines to act as a silver lining.
Export Options
About this article
Cite this article as:
Kataria Mandeep, Sethi Manisha, Kaur Jagjit, Punia Sandeep and Kumar Kuldeep, Formulation of Nanoparticles Against TB - A Review, Recent Patents on Inflammation & Allergy Drug Discovery 2015; 9 (2) . https://dx.doi.org/10.2174/1872213X09666150929105501
DOI https://dx.doi.org/10.2174/1872213X09666150929105501 |
Print ISSN 1872-213X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-2710 |
Related Articles
-
Appropriate Use of Antibiotics for the Management of Respiratory Tract
Infections
Infectious Disorders - Drug Targets Synthesis and Anti-cancer Activities of Apigenin Derivatives
Medicinal Chemistry Therapeutic Approaches Blocking Glycan Synthesis as Targeting Strategy for Malaria
Current Clinical Pharmacology 13-lncRNAs Signature to Improve Diagnostic and Prognostic Prediction of Hepatocellular Carcinoma
Combinatorial Chemistry & High Throughput Screening Inflammation and Innate Immune Response Against Viral Infections in Marine Fish
Current Pharmaceutical Design Emerging Role of Antioxidants in the Protection of Uveitis Complications
Current Medicinal Chemistry Inhaled Corticosteroids in Asthmatic Children: Are They as Safe in Infants and Preschoolers as in Older Children? A Review
Current Drug Safety Copper (II) – HisAibGly Complex and Its Superoxide Dismutase Activity (Suplementary Material)
Protein & Peptide Letters Older Adults Prescribed Methadone: A Review of the Literature Across the Life Span from Opiate Initiation to Methadone Maintenance Treatment
Current Drug Abuse Reviews Design of Lipophilic Prodrugs to Improve Drug Delivery and Efficacy
Current Drug Targets Heterocyclic Chalcone Analogues as Potential Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Discovery of Potential Dual Inhibitors Against Lipases Rv0183 and Rv3802c for Tuberculosis Therapeutics
Letters in Drug Design & Discovery Functional Interactions Between B Lymphocytes and the Innate Immune System
Infectious Disorders - Drug Targets Prevalence of Tuberculosis in a Prison in Tehran by Active Case Finding
Infectious Disorders - Drug Targets Acknowledgements and Editorial (Exploring the Role of “Treatment as Prevention”)
Current HIV Research Cytokine Therapeutics for the Treatment of Sepsis: Why has Nothing Worked?
Current Pharmaceutical Design Inhibition of Shikimate Kinase and Type II Dehydroquinase for Antibiotic Discovery: Structure-Based Design and Simulation Studies
Current Topics in Medicinal Chemistry The Impending Renaissance in Discovery & Development of Natural Products
Current Topics in Medicinal Chemistry In Vitro Antimycobacterial Activity of New 7-Chloroquinoline Derivatives
Letters in Drug Design & Discovery Streptococcal Collagen-like Protein 1 Binds Wound Fibronectin: Implications in Pathogen Targeting
Current Medicinal Chemistry