ISSN (Print):
2210-3090
ISSN (Online):
2210-3104

Recent Patents on Biomarkers

(Continued as Current Biomarkers)

Volume 5 , Issues 2, 2015


Volume 5, Issue 2 , 2015


Editorial

Meet Our Editorial Board Member:

Pp: 57-58
Author(s): Angel Garcia Martin
DOI: 10.2174/221030900502160112094416

Urinary Cytokines as Biomarkers in Glomerular Diseases

Pp: 71-80
Author(s): Maria J. Stangou and Aikaterini Papagianni
DOI: 10.2174/2210309005666151028192843

Advances in the Methodologies for the Analysis of Acute Kidney Injury Biomarkers

Pp: 81-92
Author(s): Mohammed Al Za'abi, Badreldin H. Ali and Imran Ali
DOI: 10.2174/2210309006666151123190057

Detection of Lysyl Oxidase-Like 2 (LOXL2), a Biomarker of Metastasis from Breast Cancers Using Human Blood Samples

Pp: 93-100
Author(s): Metini Janyasupab, Ying-Hui Lee, Yuan Zhang, Chen W. Liu, Jieyi Cai, Adriana Popa, Anna C. Samia, Kuan W. Wang, Jiaqiang Xu, Chi-Chang Hu, Michael K. Wendt, Barbara J. Schiemann, Cheryl L. Thompson, Yun Yen, William P. Schiemann and Chung C. Liu
DOI: 10.2174/2210309005666150804195033

Acute Injury in Natural Diet-Induced Fatty Livers - A Model for Therapy Development

Pp: 101-107
Author(s): Brian Huang, Nicholas A. E. Abbott, Linai Dacon, Siobhan McCormack, Ping Zhou, Liming Zhang, Bin Duan, Jingsong Li, Bo Zhang, Michael Yamin, Latha Paka, Itzhak D. Goldberg and Prakash Narayan
DOI: 10.2174/2210309005666151028193133

β-Crosslaps as a Marker for Bone Metastases in Renal Cell Cancer

Pp: 108-113
Author(s): Katharina Melber and Gerhard M. Oremek
DOI: 10.2174/2210309005666150918003850

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      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
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      990μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('58766425','/issue/6832/1',1,1739847583,1739847583)
      220μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 58766425 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 58766425) limit 1
      13.19msalphaeurekaselec_live_10_06_2022UserAccess.php#784
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      • 7: 58766425
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      • 11: 58766425
      • 12: 58766425
      • 13: 58766425
      • 14: 58766425
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      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • select * from `issue` where `issue_id` = '6832' order by cast(issue.title as signed) desc
      260μsalphaeurekaselec_live_10_06_2022Issue.php#160
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      Backtrace
      • 13. app/Models/Issue.php:160
      • 14. app/Http/Controllers/IssueController.php:861
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `journal` where `journal_id` = 89 limit 1
      800μsalphaeurekaselec_live_10_06_2022Journal.php#64
      Bindings
      • 0: 89
      Backtrace
      • 14. app/Models/Journal.php:64
      • 15. app/Http/Controllers/IssueController.php:863
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `volume` where `volume_id` = 1641
      200μsalphaeurekaselec_live_10_06_2022Volume.php#88
      Bindings
      • 0: 1641
      Backtrace
      • 13. app/Models/Volume.php:88
      • 14. app/Http/Controllers/IssueController.php:865
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select v.*, j.title, j.subtitle, y.year from volume v inner join journal j on v.journal_id = j.journal_id inner join year y on v.year_id = y.id where 1 and v.volume_id = 1641
      220μsalphaeurekaselec_live_10_06_2022Volume.php#292
      Backtrace
      • 11. app/Models/Volume.php:292
      • 12. app/Http/Controllers/IssueController.php:867
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 1 and a.journal_id = 89 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      1.08msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/IssueController.php:868
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 4 and a.journal_id = 89 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      870μsalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/IssueController.php:869
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select substring_index(GROUP_CONCAT(i.nicename ORDER BY i.priority SEPARATOR ', '), ',', 3) as indexing_title, COUNT(i.nicename) as indexing_occurrences from `indexing_journal` as `ij` inner join `indexing_agencies` as `i` on `ij`.`index_id` = `i`.`index_id` where `ij`.`journal_id` = 89 and `i`.`status` = 1 and `i`.`index_flag` = 1 group by `ij`.`journal_id` limit 1
      280μsalphaeurekaselec_live_10_06_2022Indexing.php#415
      Bindings
      • 0: 89
      • 1: 1
      • 2: 1
      Backtrace
      • 14. app/Models/Indexing.php:415
      • 15. app/Http/Controllers/IssueController.php:870
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `journal` where `journal_id` = 89 limit 1
      660μsalphaeurekaselec_live_10_06_2022Article.php#426
      Bindings
      • 0: 89
      Backtrace
      • 14. app/Models/Article.php:426
      • 15. app/Http/Controllers/IssueController.php:872
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as aggregate from (select a.publish_on,a.article_id,a.elocator, a.nid,a.pmid, a.title,a.altmetric_score,a.altmetric_url,a.kudos_url, j.content_type_access_id, first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"), a.graph_abs_lg_filename,a.is_epub, a.is_epub as epub, a.graph_abs_sm_filename,a.journal_id,a.volume_id,a.issue_id, a.doi,m.month,y.year, at.type_name article_type_name,a.html_filename,a.prc_filename,a.epub_filename,v.volume_name,i.title as issue, i.type as issue_type, js.js_title, js.js_id, (select GROUP_CONCAT(CONCAT(COALESCE(first_name, ""),"", last_name)) from author aa where aa.article_id = a.article_id) as authors,si.proposal_title,si.ht_code from `article` as `a` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal_section` as `js` on `js`.`js_id` = `a`.`js_id` left join `journal_access` as `j` on `a`.`article_id` = `j`.`content_type_id` and `j`.`content_type` = 'a' left join `issue` as `i` on `a`.`issue_id` = `i`.`issue_id` left join `month` as `m` on `i`.`month_id` = `m`.`id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` left join `tbl_special_issue_submission` as `si` on `si`.`reference_number` = `a`.`jms_ref_no` where a.article_status != "W" and a.is_uploaded = 1 and a.issue_id = 6832 group by `a`.`article_id`) as `aggregate_table`
      6.67msalphaeurekaselec_live_10_06_2022Article.php#469
      Backtrace
      • 16. app/Models/Article.php:469
      • 17. app/Http/Controllers/IssueController.php:872
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.publish_on,a.article_id,a.elocator, a.nid,a.pmid, a.title,a.altmetric_score,a.altmetric_url,a.kudos_url, j.content_type_access_id, first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"), a.graph_abs_lg_filename,a.is_epub, a.is_epub as epub, a.graph_abs_sm_filename,a.journal_id,a.volume_id,a.issue_id, a.doi,m.month,y.year, at.type_name article_type_name,a.html_filename,a.prc_filename,a.epub_filename,v.volume_name,i.title as issue, i.type as issue_type, js.js_title, js.js_id, (select GROUP_CONCAT(CONCAT(COALESCE(first_name, ""),"", last_name)) from author aa where aa.article_id = a.article_id) as authors,si.proposal_title,si.ht_code from `article` as `a` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal_section` as `js` on `js`.`js_id` = `a`.`js_id` left join `journal_access` as `j` on `a`.`article_id` = `j`.`content_type_id` and `j`.`content_type` = 'a' left join `issue` as `i` on `a`.`issue_id` = `i`.`issue_id` left join `month` as `m` on `i`.`month_id` = `m`.`id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` left join `tbl_special_issue_submission` as `si` on `si`.`reference_number` = `a`.`jms_ref_no` where a.article_status != "W" and a.is_uploaded = 1 and a.issue_id = 6832 group by `a`.`article_id` order by cast(a.article_no as SIGNED) asc, a.publish_on asc limit 20 offset 0
      5.91msalphaeurekaselec_live_10_06_2022Article.php#469
      Backtrace
      • 14. app/Models/Article.php:469
      • 15. app/Http/Controllers/IssueController.php:872
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '1641' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      370μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/IssueController.php:900
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '6832' and content_type = 'i' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      310μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/IssueController.php:907
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 1641) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 1641) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 1641)
      3.82msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/IssueController.php:919
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 6832) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 6832) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 6832)
      790μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/IssueController.php:932
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `journal_access` where `content_type_id` in (73001, 70579, 71385, 72055, 69333, 71386, 70489, 73002, 73003, 73004) and `content_type` = 'a' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      760μsalphaeurekaselec_live_10_06_2022ContentAccess.php#616
      Bindings
      • 0: 73001
      • 1: 70579
      • 2: 71385
      • 3: 72055
      • 4: 69333
      • 5: 71386
      • 6: 70489
      • 7: 73002
      • 8: 73003
      • 9: 73004
      • 10: a
      Backtrace
      • 13. app/Models/ContentAccess.php:616
      • 14. app/Http/Controllers/IssueController.php:945
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 6832) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 6832) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 58766425 and j.to_ip >=58766425 )) and ((j.from_date <= 1739847583 and j.to_date >= 1739847583 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 6832)
      840μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/IssueController.php:1022
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '73001' order by au.sequence
      370μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '70579' order by au.sequence
      300μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '71385' order by au.sequence
      330μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '72055' order by au.sequence
      320μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '69333' order by au.sequence
      430μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '71386' order by au.sequence
      420μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '70489' order by au.sequence
      300μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '73002' order by au.sequence
      260μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '73003' order by au.sequence
      260μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '73004' order by au.sequence
      270μsalphaeurekaselec_live_10_06_2022Author.php#137
      Backtrace
      • 11. app/Models/Author.php:137
      • 12. app/Http/Controllers/IssueController.php:1154
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `node_meta` where `nid` = 666 limit 1
      290μsalphaeurekaselec_live_10_06_2022Meta.php#30
      Bindings
      • 0: 666
      Backtrace
      • 14. app/Models/Meta.php:30
      • 15. app/Http/Controllers/IssueController.php:1181
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 89 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
      43.66msalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/IssueController.php:1188
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues from journal j join volume v on j.journal_id = v.journal_id join year y on v.year_id = y.id where j.journal_id = 89 and y.year = 2025 order by v.volume_name+0 desc limit 1
      490μsalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/IssueController.php:1189
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 89 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
      37.23msalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/IssueController.php:1191
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `subtitle` from `journal` where `continues_publication_journal` = 1
      600μsalphaeurekaselec_live_10_06_2022Article.php#1960
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/Article.php:1960
      • 14. app/Http/Controllers/IssueController.php:1197
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as aggregate from `uc_cart_products` where cart_id='9e2b9138f7d17501404390970b495460'
      280μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
        _token
        pZFTod1kOv6lsXQTb8MVJCPBSMH9pYxkqrpA5nrk
        uc_cart_id
        9e2b9138f7d17501404390970b495460
        _previous
        array:1 [ "url" => "http://alpha.eurekaselect.com/issue/6832/1" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /issue/6832/1
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:9 [ "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6IlNKam5ES1pQak1kWkpNNHlVU1NqVnc9PSIsInZhbHVlIjoiaDlwMlBzN29mSWtpdVg4UWRIY011WC85anJwcTcxbDlyU3NkU1U5VWpSaz0iLCJtYWMiOiI4ZWMyZThkZDliYTYyZTBkMjFhODgxZWZmMTg2Yzg4MzMxM2U1M2I2NWUyYWI1NzRhYjUwYzQxMjhiNTNmYWI0IiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6IlNKam5ES1pQak1kWkpNNHlVU1NqVnc9PSIsInZhbHVlIjoiaDlwMlBzN29mSWtpdVg4UWRIY011WC85anJwcTcxbDlyU3NkU1U5VWpSaz0iLCJtYWMiOiI4ZWMyZThkZDliYTYy" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "connection" => array:1 [ 0 => "keep-alive" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
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        #12025-02-18 02:59:44GET/issue/6832/11935