This book is a concise, straightforward practical guide to the clinical management of patients having drug resistant tuberculosis infections. It covers every aspect of drug resistant tuberculosis, starting from epidemiology and bacteriology to a description of the latest diagnostic tests and a list of tuberculosis drugs. Readers will find clear guidelines for selection and administration of treatment regimens for the different types of drug resistant infections as well as instructions on follow-up procedures for such cases. The book also includes a series of clinical cases illustrating some of the most frequent problems encountered by doctors while treating drug resistant tuberculosis in a clinical setting. Drug Resistant Tuberculosis: Practical guide for clinical management is a useful handbook for general practitioners and medical students interested in learning about multi drug resistant tuberculosis and pulmonary care of patients having advanced infections.

The book focuses on a global problem challenging the health systems. Trypanosoma cruzi infections are transmitted by cone-nosed triatomine bugs, by blood transfusion and congenitally from mothers to their offspring. The American Trypanosomiasis affects 20 million people; among them a significant parcel (< 1/3) will develop Chagas disease in the heart and digestive tract, where the immune system effector cells destroy target host cells. Genotype modifications resulting from transfer of minicircle sequence kDNA from the parasite into the host´s genome may explain the autoimmune pathogenesis of the disease. The book discusses various aspects of this disease and should be of interest to readers who wish to keep abreast of the developments in this field.

The addition of only two novel classes of antibiotics to fight drug resistant microorganisms in the clinic over the past three decades means that the quest for new molecules that are effective against the threat of drug resistance is now a significant issue in modern medicine. Researchers have begun to experiment on alternative therapies to combat this threat. Novel chemical agents are considered to be drugs of choice for tomorrow's clinical practice owing to their low probability to generate resistance. The first volume of Frontiers in Antimicrobial Agents describes innovative alternatives to the classical antimicrobial therapeutics, such as phage therapy, AMPs, probiotics, novel biocides, natural products and immunotherapy. Cutting-edge research is brought to the forefront, shedding light on the developments taking place to meet the challenge of drug resistant microorganisms. The volume also features information on antimicrobial approaches in veterinary medicine. The book is a useful reference for researchers, microbiologists and healthcare professionals interested in updates on antibiotic resistance and alternatives to classical antibiotic therapy.

Frontiers in Clinical Drug Research – Anti Infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti Infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The first volume of this series features reviews that cover a variety of topics including: -Bacteriophage research against gram positive bacteria -Edible vaccines -Novel antibiotics against gram negative bacteria -Antimicrobial resistance among enteric pathogens

Frontiers in Clinical Drug Research – Anti infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti-infective drug discovery and epidemiology. The second volume of this series features reviews that cover a variety of topics including: -Identification of nosocomial pathogens and antimicrobials using phenotypic techniques -Topical antimicrobials -Anti-infective drug safety -Antimicrobial resistance … and much more.

Frontiers in Clinical Drug Research - Anti infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The third volume of this series features reviews that cover a variety of topics including: -Geomic mining and metabolomic techniques for developing antimcrobials -Probiotic use in complementary antiretroviral therapy -Anti-HIV pharmaceuticals -Phytochemicals used for antimicrobial purposes - Antimicrobial photodynamic therapy (APDT)

Frontiers in Clinical Drug Research – Anti infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The fourth volume of this series features reviews that cover a variety of topics including: -Strategies to prolong antibiotic life -Catalytic antibodies for targeting rabies and influenza viruses -Antiviral therapies for arenaviruses -The role of steroids in viral infections -Monoclonal antibody manufacturing processes -Prevention and eradication of biofilms in medical devices

Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents.Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. </p><p> The fifth volume of this series features six reviews: </p><p> - Integrated Approaches for Marine Actinomycete Biodiscovery </p><p> - Therapeutic Use of Commensal Microbes: Fecal/Gut Microbiota Transplantation </p><p> - Alternative Approaches to Antimicrobials </p><p> - Nanoantibiotics: Recent Developments and Future </p><p> - Cranberry Juice and Other Functional Foods in Urinary Tract Infections in Women: A Review of Actual Evidence and Main Challenges </p><p> - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria

Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The sixth volume of this series features these interesting reviews: - Direct-acting antiviral drugs for treatment of Hepatitis C virus infection - Plant lattices as anti-infective compounds - Antimicrobial materials and devices for biomedical applications - Recent advances in the treatment of toxoplasmosis - Antimicrobial immunoglobulin prophylaxis and therapy - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria

Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. </p> The seventh volume of this series features these interesting reviews: </p> - Nucleic acid and peptide aptamers as potential antiviral drugs </p> - Host-directed, antibiotic-adjuvant combination, and antibiotic-antibiotic combinations for treating multidrug-resistant (mdr) gram-negative pathogens </p> - Bioactive substances as anti-infective strategies against clostridioides difficile </p> - Anti-toxoplasma drug discovery and natural products: a brief overview </p> - Development of antimalarial and antileishmanial drugs from amazonian biodiversity