Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The fourth volume of this series features 5 reviews: -TRP Channels: Potential Therapeutic Targets in Blood Disorders -Hypercoagulable States: Clinical Symptoms, Laboratory Markers and Management -Advanced Applications of Gene Therapy in the Treatment of Hematologic Disorders -Ferroptosis - Importance and Potential Effects in Hematological Malignancies -Clinical Application of Liquid Biopsy in Solid Tumor HCC: Prognostic, Diagnostic and Therapy Monitoring Tool

Frontiers in Clinical Drug Research - Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research - Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The fifth volume of this series features 7 reviews with a focus on thalassemia treatment and preeclampsia among other topics. - Recent advances in the diagnosis and management of pulmonary embolism - An evidence-based approach to treatment with iron chelators in transfusion- dependent thalassemia patients: present trends and future scenario - Current and future treatments of iron overload in thalassemia patients - Preeclampsia: biological and clinical aspects - Haematological modulations by fixed dose combination (FDC) of tramadol hydrochloride/paracetamol (THP) - Possible use of eculizumab in critically ill patients infected with covid-19 role of complement c5, neutrophils, and nets in the induction DIC, sepsis, and MOF hematological markers - Emerging diagnostic and therapeutic targets in preeclampsia

The spleen is an organ responsible for many biological functions, such as immunological defense, the removal of foreign particles from the blood stream, the metabolism of bilirubins, lipids and several amino acids, the control of the number and maturity of blood leukocytes and platelets and haematopoesis. This book is a collection of medical methods written exclusively to show the spleen in relation to basic sciences (anatomy and physiology) and related clinical practice and is a useful resource for clinical physicians, haematologists, oncologists, general surgeons, oncologic surgeons, trauma surgeons, resident physicians and medical students.

INTRODUCTION: <p></p> Hypertension has become a major public health problem in the last few decades. High blood pressure is a serious risk factor for premature cardiovascular disease and end-organ damage including left-ventricular hypertrophy and congestive heart failure, which in turn increases the risk of cardiovascular morbidity and mortality. <p></p> While studies of hypertension have been performed worldwide in a variety of epidemiological settings such as diabetes, renal function, obesity and thyroid disorders, there is a need to identify appropriate treatment strategies <p></p> Novel Strategies and Approaches in Hypertension introduces the reader to different aspects of hypertension treatment (environmental and occupational factors and different clinical settings that can trigger the disease). The book also covers special topics related to the use of new diagnostic biomarkers for hypertension patients, as well as endocrine and nutrition-focused approaches to treat the condition. <p></p> This reference book will be useful for medical professionals involved in the management and care of patients affected with hypertension. <p></p> [Series Introduction] <p></p> Frontiers in Hypertension presents reference works, textbooks and monographs on both fundamental and advanced topics related to the pathophysiology, diagnosis and treatment of hypertension. The series is essential reading for medical students and professionals involved in hypertension and allied subspecialty treatment programs.

Advanced Topics on Three-Dimensional Ultrasound in Obstetrics and Gynecology is a comprehensive and handy guide for sonographers, obstetricians, gynecology and radiology professionals, and all technicians working in ultrasound laboratories who are interested in taking advantage of all the resources provided by this imaging technique. The book is divided in three sections which give information on a variety of relevant topics: • Three-Dimensional Ultrasound Instrumentation and Technology. This section explains different ultrasound methods that can be used for three-dimensional imaging. It is complemented by a discussion on how to use the techniques in telemedicine. • The Use of Three-Dimensional Ultrasound During Pregnancy. This section explains the methods used to assess fetal organs, behavior and defects during different stages of pregnancy. • ‎The Use of Three-Dimensional Ultrasound When Evaluating Female Reproductive Physiology. This section covers diagnostic procedures for ovarian and uterine abnormalities and neoplasms.

Current and Future Application of Artificial Intelligence in Clinical Medicine presents updates on the application of machine learning and deep learning techniques in medical procedures. . Chapters in the volume have been written by outstanding contributors from cancer and computer science institutes with the goal of providing updated knowledge to the reader. Topics covered in the book include 1) Artificial Intelligence (AI) applications in cancer diagnosis and therapy, 2) Updates in AI applications in the medical industry, 3) the use of AI in studying the COVID-19 pandemic in China, 4) AI applications in clinical oncology (including AI-based mining for pulmonary nodules and the use of AI in understanding specific carcinomas), 5) AI in medical imaging. Each chapter presents information on related sub topics in a reader friendly format. </p> The combination of expert knowledge and multidisciplinary approaches highlighted in the book make it a valuable source of information for physicians and clinical researchers active in the field of cancer diagnosis and treatment (oncologists, oncologic surgeons, radiation oncologists, nuclear medicine physicians, and radiologists) and computer science scholars seeking to understand medical applications of artificial intelligence.

Medical Imaging Technologies and Methods for Health Care provides timely, evidence-based information that helps readers understand innovations in medical imaging. These innovations are computer / imaging based technologies which are set to have a bigger impact on the detection and management of human diseases. This volume covers: -Image processing and analyses -Computer-aided diagnosis and detection -Data mining in medical imaging -Mobile picture archiving and communications systems (PACS) -Image analytic methods in bone mineral density and detection of Alzheimer’s disease -Biomedical engineering methods applied in biomedical imaging This volume is intended as a useful resource for undergraduate and post-graduate students in medical imaging technology, radiographers, doctors, biomedical engineers, researchers and practitioners in health care.

With the success in the surgical treatment of congenital heart disease, the population of adults with congenital heart disease requiring imaging is soaring. The Role of Imaging in Adults with Congenital Heart Disease: A State-of-the-Art Review is a practical reference guide that covers each major category of congenital heart disease, providing an overview of the diseases as well as specific imaging recommendations for each disease. This Ebook has been written for cardiologists who encounter adults with congenital heart disease in clinical practice as an aid to help these patients with appropriate imaging. Additionally, the Ebook includes numerous color illustrations of the imaging modalities used, as well as a full appendix of additional images. It also includes a summary of the 2008 ACC/AHA Guidelines for Management of Adults with Congenital Heart Disease as a second appendix. It is considered essential reading for practitioners in this field.

Antibodies Applications and New Developments is an overview of the current developments of techniques and methods relating to immunodiagnostics and immunoanalysis. This eBook also deals with specialties in the fields of drug, pesticide, antigen and food contaminant detection. The volume is useful for professional immunologists and biotechnologists interested in antibody research and development.

Basic Biology and Clinical Aspects of Inflammation provides information about the critical cells and biochemical mediators involved in the complex process of inflammation. Readers are introduced to the basic scientific background on the subject, after which the book progresses towards translational research in clinical settings. Topics covered in this volume include, the modulation of inflammation during normal and chronic wound healing, altered metabolism during inflammation processes, the effect of ageing on inflammatory processes, as well as details about the underlying molecular processes behind specific clinical pathologies that are driven by excessive inflammation in the body (allergic reactions, type 2 diabetes, cardiac and vascular disease, arthritis, periodontal disease, inflammatory bowel disease and neuroinflammation). The volume also provides the latest information on pharmacotherapy for inflammation and interesting contributions towards the mathematical modeling and network analysis of inflammation. Basic Biology and Clinical Aspects of Inflammation features contributions from by a distinguished group of international researchers and clinicians highly recognized for their specific expertise in the field of inflammation. The information presented in this reference is useful to academics, medical professionals, health care regulators and pharmaceutical scientists.