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ISSN (Online): 2215-0846

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Review Article

Compendium of Salvia officinalis: An Overview

Author(s): Ruchi Khare, Neeraj Upmanyu*, Tripti Shukla, Vishal Jain and Megha Jha

Volume 6, Issue 4, 2020

Page: [300 - 311] Pages: 12

DOI: 10.2174/2215083805666190723095043

Price: $65

Abstract

The medicinal plants have enormous commercial potential throughout the globe. In the herbal boom worldwide, it is estimated that high quality phyto-medicinals will provide safe and effective medication. In India, Ayurveda, Siddha, Unani etc. consist of large number of herbal remedies, being used from ancient times. Many plant species containing active constituents that have a direct pharmacological action on the body. This plant Sage (Salvia officinalis Linn) is historically well known from the early 1960s till now by its therapeutic and culinary applications due to its high economic value. The plant is reported to contain alkaloids, triterpenoid, steroids, Phenolic compounds and essential oils. Sage plant is a rich source of antioxidant properties, for this reason sage has found increasing application in food industry. The core purpose of this review is to emphasize the origin, morphology, Phytochemistry and pharmacological aspects of Sage (Salvia officinalis Linn).

Keywords: Tejpaat, sage, terpenoids, flavonoids, essential oils, antimicrobial, anticancer, flavoring agent.

Graphical Abstract

[1]
Mukherjee PK. Quality Control of Herbal Drugs 1999; 14: 1-3.
[2]
Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prod 2007; 70(3): 461-77.
[http://dx.doi.org/10.1021/np068054v]
[3]
Nadkarni KM. Indian Materia Medica, Bombay. Popular Prakashan 1986; I: 545.
[4]
Udichi K, Ashok D, Jain CP, Nema RK. Herbals: History, standardization and validation. Planta Indica 2007 October; 3(4): 23-6.
[5]
Barbu I, Ambarus S, Brezeanu C, Stan N. The 6n onescu de la Brad Iasi In: 2005; I (48).
[6]
Said-Al Ahl H, Hussein MS, Gendy AS, Tkachenko KG. Quality of sage (Salvia officinalis L.) essential oil grown in Egypt. Int J Plant Sci Ecol 2015; 1(4): 119-23.
[7]
Abdelkader M, Ahcen B, Rachid D, Hakim H. Phytochemical study and biological activity of sage (Salvia officinalis L.). Int J Bio Biomol Agric Food Biotechnol Eng 2014; 8(11): 1231-5.
[8]
Harley RM, Atkins S, Budantsev AL, et al. Labiatae Flowering Plants Dicotyledons. Berlin, Heidelberg: Springer 2004; pp. 167-275.
[http://dx.doi.org/10.1007/978-3-642-18617-2_11]
[9]
Kamatou GP, Makunga NP, Ramogola WP, Viljoen AM. South African Salvia species: a review of biological activities and phytochemistry. J Ethnopharmacol 2008; 119(3): 664-72.
[http://dx.doi.org/10.1016/j.jep.2008.06.030]
[10]
Nunthaboot N, Lugsanangarm K, Kokpol S, Abd-Elazem IS. Binding mode prediction of biologically active compounds from plant Salvia Miltiorrhiza as integrase inhibitor. Bioinformation 2013; 9(8): 426.
[http://dx.doi.org/10.6026/97320630009426]
[11]
Narayanan N, Thangavelu L. Salvia officinalis in dentistry. Dent Hypotheses 2015; 6(1): 27.
[http://dx.doi.org/10.4103/2155-8213.150870]
[12]
Floridata Plant Encyclopedia. In: 609.
[13]
Delamare AP, Moschen-Pistorello IT, Artico L, Atti-Serafini L, Echeverrigaray S. Antibacterial activity of the essential oils of Salvia officinalis L. and Salvia triloba L. cultivated in South Brazil. Food Chem 2007; 100(2): 603-8.
[http://dx.doi.org/10.1016/j.foodchem.2005.09.078]
[14]
Purple Sage Medicinal herbs, herbs and herbalism 2003. Available from. http://www.purplesage.org.uk
[15]
Mirjalili MH, Salehi P, Sonboli A, Vala MM. Essential oil variation of Salvia officinalis aerial parts during its phenological cycle. Chem Nat Compd 2006; 42(1): 19-23.
[http://dx.doi.org/10.1007/s10600-006-0027-4]
[16]
Ayurveda Always. A Sister Concern of Planet Ayurveda 1992; 5(32): 177.
[17]
Clebsch B. The New Book of Salvias: Sages for Every Garden. Portland, or: Timber Press 344p-illus, col illus 2003.
[18]
Behradmanesh S, Derees F, Rafieian-Kopaei M. Effect of Salvia officinalis on diabetic patients. J Renal Inj Prev 2013; 2(2): 51.
[19]
Species Board India. Ministry of Commerce and Industry, Govt. of India, Last Update on 18/11/ 2015.
[20]
Plants home, USDA gov, NRCS, Last modified 25/06/2018 53: 483-7.
[21]
Watters LL. An Analytical Investigation of Garden Sage (Salvia Officinalis, Linné). Columbia University 1901.
[22]
Badiee P, Nasirzadeh AR, Motaffaf M. Comparison of Salvia officinalis L. essential oil and antifungal agents against candida species. J Pharma Technol Drug Res 2012; 1(1): 7.
[http://dx.doi.org/10.7243/2050-120X-1-7]
[23]
Capek P, Hríbalová V. Water-soluble polysaccharides from Salvia officinalis L. possessing immunomodulatory activity. Phytochemistry 2004; 65(13): 1983-92.
[http://dx.doi.org/10.1016/j.phytochem.2004.05.020]
[24]
El Hadri A, del Río MÁ, Sanz J, et al. Cytotoxic activity of α-humulene and transcaryophyllene from Salvia officinalis in animal and human tumor cells. An R Acad Nac Farm 2010; 73(3): 343-56.
[25]
Hayouni EA, Chraief I, Abedrabba M, et al. Tunisian Salvia officinalis L. and Schinus molle L. essential oils: their chemical compositions and their preservative effects against Salmonella inoculated in minced beef meat. Int J Food Microbiol 2008; 125(3): 242-51.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2008.04.005]
[26]
Länger R, Mechtler C, Jurenitsch J. Composition of the essential oils of commercial samples of Salvia officinalis L. and S. fruticosa Miller: A comparison of oils obtained by extraction and steam distillation. Phytochem Anal 1996; 7(6): 289-93.
[http://dx.doi.org/10.1002/(SICI)1099-1565(199611)7:6<289:AID-PCA318>3.0.CO;2-7]
[27]
Lima CF, Carvalho F, Fernandes E, et al. Evaluation of toxic/protective effects of the essential oil of Salvia officinalis on freshly isolated rat hepatocytes. Toxicol In Vitro 2004; 18(4): 457-65.
[http://dx.doi.org/10.1016/j.tiv.2004.01.001]
[28]
Lima CF, Andrade PB, Seabra RM, Fernandes-Ferreira M, Pereira-Wilson C. The drinking of a Salvia officinalis infusion improves liver antioxidant status in mice and rats. J Ethnopharmacol 2005; 97(2): 383-9.
[http://dx.doi.org/10.1016/j.jep.2004.11.029]
[29]
Lima CF, Fernandes-Ferreira M, Pereira-Wilson C. Drinking of Salvia officinalis tea increases CCl4-induced hepatotoxicity in mice. Food Chem Toxicol 2007; 45(3): 456-64.
[http://dx.doi.org/10.1016/j.fct.2006.09.009.]
[30]
Mitić-Ćulafić D, Vuković-Gačić BS, Knežević-Vukčević JB, Stanković S, Simić DM. Comparative study on the antibacterial activity of volatiles from sage (Salvia officinalis L.). Arch Biol Sci 2005; 57(3): 173-8.
[http://dx.doi.org/10.2298/ABS0503173M]
[31]
Russo A, Formisano C, Rigano D, et al. Chemical composition and anticancer activity of essential oils of Mediterranean sage (Salvia officinalis L.) grown in different environmental conditions. Food Chem Toxicol 2013; 55: 42-7.
[http://dx.doi.org/10.1016/j.fct.2012.12.036]
[32]
Seidel V. Initial and bulk extraction. In:Natural products isolation. Humana Press 2006; pp. 27-46.
[http://dx.doi.org/10.1385/1-59259-955-9:27]
[33]
Veličković DT, Ranđelović NV, Ristić MS, Veličković AS, Šmelcerović AA. Chemical constituents and antimicrobial activity of the ethanol extracts obtained from the flower, leaf and stem of Salvia officinalis L. J Serb Chem Soc 2003; 68(1): 17-24.
[http://dx.doi.org/10.2298/JSC0301017V]
[34]
Venskutonis PR. Effect of drying on the volatile constituents of thyme (Thymus vulgaris L.) and sage (Salvia officinalis L.). Food Chem 1997; 59(2): 219-27.
[http://dx.doi.org/10.1016/S0308-8146(96)00242-7]
[35]
Wang M, Li J, Rangarajan M, et al. Antioxidative phenolic compounds from sage (Salvia officinalis). J Agric Food Chem 1998; 46(12): 4869-73.
[http://dx.doi.org/10.1021/jf980614b]
[36]
Wang M, Kikuzaki H, Zhu N, Sang S, Nakatani N, Ho CT. Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.). J Agric Food Chem 2000; 48(2): 235-8.
[http://dx.doi.org/10.1021/jf990761p]
[37]
Couladis M, Tzakou O, Mimica‐Dukić N, Jančić R, Stojanović D. Essential oil of Salvia officinalis L. from Serbia and Montenegro. Flavour Fragrance J 2002; 17(2): 119-26.
[http://dx.doi.org/10.1002/ffj.1065]
[38]
Durling NE, Catchpole OJ, Grey JB, et al. Extraction of phenolics and essential oil from dried sage (Salvia officinalis) using ethanol-water mixtures. Food Chem 2007; 101(4): 1417-24.
[http://dx.doi.org/10.1016/j.foodchem.2006.03.050]
[39]
Pharmacopoeia BH. British Herbal Manufacturers Association. Esher, Surrey: BHMA 1983.
[40]
Lamaison JL, Petitjean-Freytet C, Carnat A. [Medicinal Lamiaceae with antioxidant properties, a potential source of rosmarinic acid]. Pharm Acta Helv 1991; 66(7): 185-8.
[41]
Cuvelier ME, Berset C, Richard H. Antioxidant constituents in sage (Salvia officinalis). J Agric Food Chem 1994; 42(3): 665-9.
[http://dx.doi.org/10.1021/jf00039a012]
[42]
Lawrence MB. Progress in essential oils-sage oil, fennel oil and cardamom oil. Perfum Flavor 1998; 23(2): 47-57.
[43]
Croteau R, Alonso WR, Koepp AE, Johnson MA. Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase. Arch Biochem Biophys 1994; 309(1): 184-92.
[http://dx.doi.org/10.1006/abbi.1994.1101]
[44]
Wise ML, Savage TJ, Katahira E, Croteau R. Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase. J Biol Chem 1998; 273(24): 14891-9.
[http://dx.doi.org/10.1074/jbc.273.24.14891]
[45]
Figueiredo AC, Barroso JG, Pedro LG, Scheffer JJ. Factors affecting secondary metabolite production in plants: Volatile components and essential oils. Flavour Fragrance J 2008; 23(4): 213-26.
[http://dx.doi.org/10.1002/ffj.1875]
[46]
Grausgruber-Gröger S, Schmiderer C, Steinborn R, Novak J. Seasonal influence on gene expression of monoterpene synthases in Salvia officinalis (Lamiaceae). J Plant Physiol 2012; 169(4): 353-9.
[http://dx.doi.org/10.1016/j.jplph.2011.11.004]
[47]
Horváthová E, Srančíková A, Regendová-Sedláčková E, et al. Enriching the drinking water of rats with extracts of Salvia officinalis and Thymus vulgaris increases their resistance to oxidative stress. Mutagenesis 2015; 31(1): 51-9.
[48]
Cuvelier ME, Richard H, Berset C. Antioxidative activity and phenolic composition of pilot-plant and commercial extracts of sage and rosemary. J Am Oil Chem Soc 1996; 73(5): 645.
[http://dx.doi.org/10.1007/BF02518121]
[49]
Azevedo MI, Pereira AF, Nogueira RB, et al. The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplatin-induced chronic painful peripheral neuropathy. Mol Pain 2013; 9(1): 53.
[http://dx.doi.org/10.1186/1744-8069-9-53]
[50]
Fonseca JP, Farinha TO, do Pinho RJ, et al. Anti-inflammatory activity of Salvia officinalis L. J Med Plants Res 2012; 6(35): 4934-9.
[51]
Bauer J, Kuehnl S, Rollinger JM, et al. Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1. J Pharmacol Exp Ther 2012; 342(1): 169-76.
[http://dx.doi.org/10.1124/jpet.112.193847]
[52]
Rodrigues MR, Kanazawa LK, das Neves TL, et al. Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice. J Ethnopharmacol 2012; 139(2): 519-26.
[http://dx.doi.org/10.1016/j.jep.2011.11.042]
[53]
Abad AN, Nouri MH, Tavakkoli F. Effect of Salvia officinalis hydroalcoholic extract on vincristine-induced neuropathy in mice. Chin J Nat Med 2011; 9(5): 354-8.
[54]
Mansourabadi AH, Sadeghi M, Razavi N, Rezvani E. Anti-inflammatory and analgesic properties of salvigenin, Salvia officinalis flavonoid extracted. Adv Herbal Med 2015; 1(3): 31-41.
[55]
Hubbert M, Sievers H, Lehnfeld R, Kehrl W. Efficacy and tolerability of a spray with Salvia officinalis in the treatment of acute pharyngitis - a randomised, double-blind, placebo-controlled study with adaptive design and interim analysis. Eur J Med Res 2006; 11(1): 20-6.
[56]
Ou MC, Hsu TF, Lai AC, Lin YT, Lin CC. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet Gynaecol Res 2012; 38(5): 817-22.
[http://dx.doi.org/10.1111/j.1447-0756.2011.01802.x]
[57]
Muttalib LY, Naqishbandi AM. Antibacterial and phytochemical study of Iraqi Salvia officinalis leave extracts. Iraqi J Pharm Sci 2017; 21(1): 93-7. (ISSN: 1683-3597, ESSN: 2521-3512)
[58]
Stefanović OD, Stanojević DD, Comić LR. Synergistic antibacterial activity of Salvia officinalis and Cichorium intybus extracts and antibiotics. Acta Pol Pharm 2012; 69(3): 457-63.
[59]
Generalić I, Skroza D, Šurjak J, et al. Seasonal variations of phenolic compounds and biological properties in sage (Salvia officinalis L.). Chem Biodivers 2012; 9(2): 441-57.
[http://dx.doi.org/10.1002/cbdv.201100219]
[60]
Baddar NW, Aburjai TA, Taha MO, Disi AM. Thujone corrects cholesterol and triglyceride profiles in diabetic rat model. Nat Prod Res 2011; 25(12): 1180-4.
[http://dx.doi.org/10.1080/14786419.2010.496116]
[61]
Christensen KB, Jørgensen M, Kotowska D, Petersen RK, Kristiansen K, Christensen LP. Activation of the nuclear receptor PPARγ by metabolites isolated from sage (Salvia officinalis L.). J Ethnopharmacol 2010; 132(1): 127-33.
[http://dx.doi.org/10.1016/j.jep.2010.07.054]
[62]
Vuković-Gacić B, Nikcević S, Berić-Bjedov T, Knezević-Vukcević J, Simić D. Antimutagenic effect of essential oil of sage (Salvia officinalis L.) and its monoterpenes against UV-induced mutations in Escherichia coli and Saccharomyces cerevisiae. Food Chem Toxicol 2006; 44(10): 1730-8.
[http://dx.doi.org/10.1016/j.fct.2006.05.011]
[63]
Ramos AA, Pedro D, Collins AR, Pereira-Wilson C. Protection by Salvia extracts against oxidative and alkylation damage to DNA in human HCT15 and CO115 cells. J Toxicol Environ Health A 2012; 75(13-15): 765-75.
[http://dx.doi.org/10.1080/15287394.2012.689804]]
[64]
Janicsák G, Zupkó I, Nikolovac MT, et al. Bioactivity-guided study of antiproliferative activities of Salvia extracts. Nat Prod Commun 2011; 6(5): 575-9.
[http://dx.doi.org/10.1177/1934578X1100600501]
[65]
Pedro DF, Ramos AA, Lima CF, Baltazar F, Pereira-Wilson C. Colon cancer chemoprevention by sage tea drinking: Decreased DNA damage and cell proliferation. Phytother Res 2016; 30(2): 298-305.
[http://dx.doi.org/10.1002/ptr.5531]
[66]
Garcia CS, Menti C, Lambert AP, et al. Pharmacological perspectives from Brazilian Salvia officinalis (Lamiaceae): antioxidant, and antitumor in mammalian cells. An Acad Bras Cienc 2016; 88(1): 281-92.
[http://dx.doi.org/10.1590/0001-3765201520150344]
[67]
Jedinák A, Mucková M, Kost’álová D, Maliar T, Mašterová I. Antiprotease and antimetastatic activity of ursolic acid isolated from Salvia officinalis. Z Naturforsch C 2006; 61(11-12): 777-82.
[http://dx.doi.org/10.1515/znc-2006-11-1203]
[68]
Sertel S, Eichhorn T, Plinkert PK, Efferth T. [Anticancer activity of Salvia officinalis essential oil against HNSCC cell line (UMSCC1)]. HNO 2011; 59(12): 1203-8.
[http://dx.doi.org/10.1007/s00106-011-2274-3]
[69]
Xavier CP, Lima CF, Fernandes-Ferreira M, Pereira-Wilson C. Salvia fruticosa, Salvia officinalis, and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway. Nutr Cancer 2009; 61(4): 564-71.
[http://dx.doi.org/10.1080/01635580802710733]
[70]
Kontogianni VG, Tomic G, Nikolic I, et al. Phytochemical profile of Rosmarinus officinalis and Salvia officinalis extracts and correlation to their antioxidant and anti-proliferative activity. Food Chem 2013; 136(1): 120-9.
[http://dx.doi.org/10.1016/j.foodchem.2012.07.091]
[71]
Russo A, Formisano C, Rigano D, et al. Chemical composition and anticancer activity of essential oils of Mediterranean sage (Salvia officinalis L.) grown in different environmental conditions. Food Chem Toxicol 2013; 55: 42-7.
[http://dx.doi.org/10.1016/j.fct.2012.12.036]
[72]
Yesil-Celiktas O, Sevimli C, Bedir E, Vardar-Sukan F. Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines. Plant Foods Hum Nutr 2010; 65(2): 158-63.
[http://dx.doi.org/10.1007/s11130-010-0166-4]
[73]
Keshavarz M, Mostafaie A, Mansouri K, Bidmeshkipour A, Motlagh HR, Parvaneh S. In vitro and ex vivo antiangiogenic activity of Salvia officinalis. Phytother Res 2010; 24(10): 1526-31.
[http://dx.doi.org/10.1002/ptr.3168]
[74]
Obulesu M, Rao DM. Effect of plant extracts on Alzheimer’s disease: An insight into therapeutic avenues. J Neurosci Rural Pract 2011; 2(1): 56.
[http://dx.doi.org/10.4103/0976-3147.80102]
[75]
Akhondzadeh S, Noroozian M, Mohammadi M, Ohadinia S, Jamshidi AH, Khani M. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther 2003; 28(1): 53-9.
[http://dx.doi.org/10.1046/j.1365-2710.2003.00463.x]
[76]
Hubbert M, Sievers H, Lehnfeld R, Kehrl W. Efficacy and tolerability of a spray with Salvia officinalis in the treatment of acute pharyngitis - a randomised, double-blind, placebo-controlled study with adaptive design and interim analysis. Eur J Med Res 2006; 11(1): 20-6.
[77]
George J, Hegde S, Rajesh KS, Kumar A. The efficacy of a herbal-based toothpaste in the control of plaque and gingivitis: a clinico-biochemical study. Indian J Dent Res 2009; 20(4): 480.
[http://dx.doi.org/10.4103/0970-9290.59460]
[78]
Behradmanesh S, Derees F, Rafieian-Kopaei M. Effect of Salvia officinalis on diabetic patients. J Renal Inj Prev 2013; 2(2): 51.
[79]
Eidi M, Eidi A, Zamanizadeh H. Effect of Salvia officinalis L. leaves on serum glucose and insulin in healthy and streptozotocin-induced diabetic rats. J Ethnopharmacol 2005; 100(3): 310-3.
[http://dx.doi.org/10.1016/j.jep.2005.03.008]
[80]
Eidi A, Eidi M. Antidiabetic effects of sage (Salvia officinalis L.) leaves in normal and streptozotocin-induced diabetic rats. Diabetes Metab Syndr 2009; 3(1): 40-4.
[http://dx.doi.org/10.1016/j.dsx.2008.10.007]
[81]
Khattab HA, Mohamed RA, Hashemi JM. Evaluation of hypoglycemic activity of Salvia officinalis L. (Sage) infusion on streptozotocin-induced diabetic rats. J Am Sci 2012; 8(11): 411-6.
[82]
Lima CF, Azevedo MF, Araujo R, Fernandes-Ferreira M, Pereira-Wilson C. Metformin-like effect of Salvia officinalis (common sage): is it useful in diabetes prevention? Br J Nutr 2006; 96(2): 326-33.
[http://dx.doi.org/10.1079/BJN20061832]
[83]
Christensen KB, Jørgensen M, Kotowska D, Petersen RK, Kristiansen K, Christensen LP. Activation of the nuclear receptor PPARγ by metabolites isolated from sage (Salvia officinalis L.). J Ethnopharmacol 2010; 132(1): 127-33.
[http://dx.doi.org/10.1016/j.jep.2010.07.054]
[84]
Shafiee-Nick R, Ghorbani A, Bagheri VF, Rakhshandeh H. Chronic administration of a combination of six herbs inhibits the progression of hyperglycemia and decreases serum lipids and aspartate amino transferase activity in diabetic rats. Adv Pharmacol Sci 2012; 2012
[http://dx.doi.org/10.1155/2012/789796]
[85]
Hernández-Saavedra D, Pérez-Ramírez IF, Ramos-Gómez M, Mendoza-Díaz S, Loarca-Piña G, Reynoso-Camacho R. Phytochemical characterization and effect of Calendula officinalis, Hypericum perforatum, and Salvia officinalis infusions on obesity-associated cardiovascular risk. Med Chem Res 2016; 25(1): 163-72.
[http://dx.doi.org/10.1007/s00044-015-1454-1]
[86]
Govindaraj J, Pillai S. Rosmarinic acid modulates the antioxidant status and protects pancreatic tissues from glucolipotoxicity mediated oxidative stress in high-fat diet: streptozotocin-induced diabetic rats. Mol Cell Biochem 2015; 404(1-2): 143-59.
[http://dx.doi.org/10.1007/s11010-015-2374-6]
[87]
Seo S, Lee MS, Chang E, et al. Rutin increases muscle mitochondrial biogenesis with AMPK activation in high-fat diet-induced obese rats. Nutrients 2015; 7(9): 8152-69.
[http://dx.doi.org/10.3390/nu7095385]
[88]
Moss L, Rouse M, Wesnes KA, Moss M. Differential effects of the aromas of Salvia species on memory and mood. Hum Psychopharmacol 2010; 25(5): 388-96.
[http://dx.doi.org/10.1002/hup.1129]
[89]
Moss M, Rouse M, Moss L. Aromas of Salvia species enhances everyday prospective memory performance in healthy young adults. Adv Chem Eng Sci 2014; 4: 339-46.
[http://dx.doi.org/10.4236/aces.2014.43037]
[90]
Scholey AB, Tildesley NT, Ballard CG, et al. An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers. Psychopharmacology (Berl) 2008; 198(1): 127-39.
[http://dx.doi.org/10.1007/s00213-008-1101-3]
[91]
Eidi M, Eidi A, Bahar M. Effects of Salvia officinalis L. (sage) leaves on memory retention and its interaction with the cholinergic system in rats. Nutrition 2006; 22(3): 321-6.
[http://dx.doi.org/10.1016/j.nut.2005.06.010]
[92]
Gomar A, Hosseini A, Mirazi N. Evaluation of Salvia officinalis L.(sage) leaves on morphine‐induced memory impairment in adult male rats. Focus Altern Complement Ther 2014; 19(3): 156-62.
[http://dx.doi.org/10.1111/fct.12132]
[93]
Sage C. Spice board India [Online]. 2012 July 23 Cited 2012 July]; Accessed from URL: http://www.indianspices.com/ html/s0625sage.htm
[94]
Behradmanesh S, Derees F, Rafieian-Kopaei M. Effect of Salvia officinalis on diabetic patients. J Renal Inj Prev 2013; 2(2): 51.
[95]
Estevez M, Ramirez R, Ventanas S, Cava R. Sage and rosemary essential oils versus BHT for the inhibition of lipid oxidative reactions in liver pâté. Lebensm Wiss Technol 2007; 40(1): 58-65.
[http://dx.doi.org/10.1016/j.lwt.2005.07.010]
[96]
Klaus A, Beatović D, Nikšić M, Jelačić S, Petrović T. Antibacterial activity of aromatic plants essential oils from Serbia against the Listeria monocytogenes. J Agric Sci Belgrade 2009; 54(2): 95-104.
[http://dx.doi.org/10.2298/JAS0902095K]

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