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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Editorial

DNA Damaging Agents in Cancer Therapy

Author(s): Fei You and Changshou Gao

Volume 19, Issue 9, 2019

Page: [690 - 690] Pages: 1

DOI: 10.2174/156802661909190620154618

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[1]
Collado, M.; Gil, J.; Efeyan, A.; Guerra, C.; Schuhmacher, A.J.; Barradas, M.; Benguría, A.; Zaballos, A.; Flores, J.M.; Barbacid, M.; Beach, D.; Serrano, M. Tumour biology: senescence in premalignant tumours. Nature, 2005, 436(7051), 642.
[2]
Braig, M.; Lee, S.; Loddenkemper, C.; Rudolph, C.; Peters, A.H.; Schlegelberger, B.; Stein, H.; Dörken, B.; Jenuwein, T.; Schmitt, C.A. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature, 2005, 436(7051), 660-665.
[3]
Michaloglou, C.; Vredeveld, L.C.; Soengas, M.S.; Denoyelle, C.; Kuilman, T.; van der Horst, C.M.; Majoor, D.M.; Shay, J.W.; Mooi, W.J.; Peeper, D.S. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature, 2005, 436(7051), 720-724.
[4]
Chen, Z.; Trotman, L.C.; Shaffer, D.; Lin, H.K.; Dotan, Z.A.; Niki, M.; Koutcher, J.A.; Scher, H.I.; Ludwig, T.; Gerald, W.; Cordon-Cardo, C.; Pandolfi, P.P. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 2005, 436(7051), 725-730.
[5]
Diethelm-Varela, B.; Ai, Y.; Liang, D.; Xue, F. Nitrogen mustards as anticancer chemotherapies: historic perspective, current developments, and future trends. Curr. Top. Med. Chem., 2018, 19(9), 691-712.
[6]
You, F.; Gao, C. Topoisomerase inhibitors and targeted delivery in cancer therapy. Curr. Top. Med. Chem., 2018, 19(9), 713-729.
[7]
Wang, W.; Tse-Dinh, Y-C. Recent advances in use of topoisomerase inhibitors in combination cancer therapy. Curr. Top. Med. Chem., 2018, 19(9), 730-740.
[8]
Cailleau, T.; Adam, L.R.; Arora, N.; Kang, G-D.; Masterson, L.; Patel, N.; Hartley, J.A.; Mao, S.; Harper, J.; Howard, P.W. Potentiation of PBD dimers by lipophilicity manipulation. Curr. Top. Med. Chem., 2018, 19(9), 741-752.

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