Abstract
Background: Non-tuberculous mycobacterial (NTM) infections have been drawing interest recently because of their rising incidence not only in immunocompromised but also in immunocompetent individuals. These are underdiagnosed in India, due to the lack of awareness and a low index of suspicion. In regions endemic for tuberculosis (TB) such as India, presumptive anti-tubercular treatment (ATT) is often prescribed. Non-response of NTM to the treatment may be wrongly ascribed to multidrug-resistant tuberculosis. This emphasizes the need to correctly identify them before initiating therapy.
Case Study: We describe the case of a young, healthy female patient who developed cervical lymphadenitis and was given presumptive ATT. Microbiological examination of aspirate revealed M. fortuitum. This not only rectified the course of treatment resulting in complete cure, but also spared the patient from significant side effects of ATT. This case is an awakening call for clinicians to avoid presumptive ATT.
Keywords: Immunocompetent, Mycobacterium fortuitum, cervical lymphadenitis, antitubercular treatment, submandibular lymphadenitis, non-tuberculous mycobacteria.
Infectious Disorders - Drug Targets
Title:Submandibular Lymphadenitis in an Immunocompetent Female: Microbiological Confirmation is Need of the Hour
Volume: 20 Issue: 6
Author(s): Lipika Singhal, Pooja Kumari, Menal Gupta*, Kranti Garg and Jagdish Chander
Affiliation:
- Department of Microbiology, Government Medical College and Hospital, Sector- 32, Chandigarh,India
Keywords: Immunocompetent, Mycobacterium fortuitum, cervical lymphadenitis, antitubercular treatment, submandibular lymphadenitis, non-tuberculous mycobacteria.
Abstract:
Background: Non-tuberculous mycobacterial (NTM) infections have been drawing interest recently because of their rising incidence not only in immunocompromised but also in immunocompetent individuals. These are underdiagnosed in India, due to the lack of awareness and a low index of suspicion. In regions endemic for tuberculosis (TB) such as India, presumptive anti-tubercular treatment (ATT) is often prescribed. Non-response of NTM to the treatment may be wrongly ascribed to multidrug-resistant tuberculosis. This emphasizes the need to correctly identify them before initiating therapy.
Case Study: We describe the case of a young, healthy female patient who developed cervical lymphadenitis and was given presumptive ATT. Microbiological examination of aspirate revealed M. fortuitum. This not only rectified the course of treatment resulting in complete cure, but also spared the patient from significant side effects of ATT. This case is an awakening call for clinicians to avoid presumptive ATT.
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Cite this article as:
Singhal Lipika , Kumari Pooja , Gupta Menal *, Garg Kranti and Chander Jagdish , Submandibular Lymphadenitis in an Immunocompetent Female: Microbiological Confirmation is Need of the Hour, Infectious Disorders - Drug Targets 2020; 20 (6) . https://dx.doi.org/10.2174/1871526519666190619150549
DOI https://dx.doi.org/10.2174/1871526519666190619150549 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
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