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Review Article

来自深海衍生微生物的次级代谢产物

卷 27, 期 36, 2020

页: [6244 - 6273] 页: 30

弟呕挨: 10.2174/0929867326666190618153950

价格: $65

摘要

来自深海的微生物是海洋天然产物的丰富来源，具有独特的化学结构和生物活性。在本文中，我们将回顾深海(≥1000 m)微生物天然产物领域内的优秀研究成果，截至2017年底共产生442种化合物。大约60%的这些结构显示出各种各样的生物活性，超过30%显示出细胞毒性功能。本文重点综述了近年来深海源微生物产生次生代谢物的研究成果，包括微生物的结构特征、生物活性以及来源微生物的生物起源和分类特征，其中，我们希望能对从深海环境中获得的小分子提供更全面的了解，并有助于正在进行的从深海衍生微生物中寻找新型药物制剂的学术努力。

关键词: 深海微生物，次生代谢物，天然产物，生物活性，细胞毒性，抗菌

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