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Review Article

外泌体：人类疾病生物标志物的新兴来源

卷 19, 期 6, 2019

页: [387 - 394] 页: 8

弟呕挨: 10.2174/1566524019666190429144310

价格: $65

摘要

外泌体是30-120nm长的内吞膜衍生的囊泡，其由各种类型的细胞分泌并稳定存在于体液中，例如血浆，尿液，唾液和母乳。 外来体参与细胞间通讯。 最近的累积研究表明，外泌体可以作为疾病诊断和预后的新型生物标志物。 在这里，我们回顾了外泌体的生物学特征，外泌体分离和鉴定技术，以及外泌体生物标志物鉴定的进展，突出了外泌体与人类疾病的相关性和意义以及转化医学的巨大潜力。

关键词: 外泌体，分离，生物标志物，蛋白质，RNA，诊断。

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