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Review Article

壳聚糖及其衍生物的生物医学应用研究进展

卷 27, 期 18, 2020

页: [3023 - 3045] 页: 23

弟呕挨: 10.2174/0929867326666190405151538

价格: $65

摘要

壳聚糖是第二丰富的天然多糖。它具有生物降解性、生物相容性、无毒性等独特特性。由于其主链上有游离胺基和羟基，壳聚糖可以进行进一步的化学修饰以生成具有附加生物医学功能的壳聚糖衍生物。壳聚糖和CDs可以制成各种形式，包括纳米粒子(NPs)、胶束、水凝胶、纳米复合材料和纳米螯合物。因此，壳聚糖和CDs近年来在生物医学领域得到了广泛的应用。本文主要介绍了近五年来壳聚糖和CDs在癌症治疗/诊断、分子生物传感、病毒感染和组织工程等方面的突出应用。并对壳聚糖今后的研究方向进行了展望。

关键词: 壳聚糖，壳聚糖衍生物，纳米粒子，胶束，水凝胶，纳米复合材料，纳米螯合物，癌症治疗，诊断，分子生物传感，病毒感染，组织工程。

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