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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Case Report

Misdiagnosis of Intrahepatic Biliary Cystadenoma Located in the Caudate Lobe: A Case Report

Author(s): Huan-Jian Xu, Zhi-Yang Zhu, Jian-Hua Yu, Wei Wang and Zhi-Hong Shen*

Volume 22, Issue 4, 2019

Page: [276 - 279] Pages: 4

DOI: 10.2174/1386207322666190402162614

Price: $65

Abstract

Background: Intrahepatic Biliary Cystadenoma (IBC) is rare but has a high incidence of misdiagnosis, especially for experienceless surgeons.

Case: We report a case of IBC located in the caudate lobe and described a typical procedure of misdiagnosing this disease. Finally, the patient was successfully cured, but the procedure of misdiagnosis should attract attention. IBC and atypical biopsy for histological examination are the most important causes of misdiagnosis. Recurrent cystic lesions of the liver and repeated increases in CA 19-9 may suggest a "liver cyst", which is a misdiagnosis.

Conclusion: The experience and lessons of misdiagnosis, in this case, may help other clinicians diagnose the rare disease accurately.

Keywords: Intrahepatic biliary cystadenoma, hepatic cyst, misdiagnosis, caudate lobe, cystic lesions, tumor.

[1]
Davies, W.; Chow, M.; Nagorney, D. Extrahepatic biliary cystadenomas and cystadenocarcinoma. Report of seven cases and review of the literature. Ann. Surg., 1995, 222, 619-625.
[2]
Lewis, W.D.; Jenkins, R.L.; Rossi, R.L.; Munson, L. ReMine, S.G.; Cady, B.; Braasch, J.W.; McDermott, W.V. Surgical treatment of biliary cystadenoma. A report of 15 cases. Arch. Surg., 1988, 123, 563-568.
[3]
Ramacciato, G.; Nigri, G.R.; D’Angelo, F.; Aurello, P.; Bellagamba, R.; Colarossi, C.; Pilozzi, E.; Del Gaudio, M. Emergency laparotomy for misdiagnosed biliary cystadenoma originating from caudate lobe. World J. Surg. Oncol., 2006, 4, 76.
[4]
Dixon, E.; Sutherland, F.R.; Mitchell, P.; McKinnon, G.; Nayak, V. Cystadenomas of the liver: A spectrum of disease. Can. J. Surg., 2001, 44, 371-376.
[5]
Devaney, K.; Goodman, Z.D.; Ishak, K.G. Hepatobiliary cystadenoma and cystadenocarcinoma. A light microscopic and immunohistochemical study of 70 patients. Am. J. Surg. Pathol., 1994, 18, 1078-1091.
[6]
Stanley, J.; Vujic, I.; Schabel, S.I.; Gobien, R.P.; Reines, H.D. Evaluation of biliary cystadenoma and cystadenocarcinoma. Gastrointest. Radiol., 1983, 8, 245-248.
[7]
Kazama, S.; Hiramatsu, T.; Kuriyama, S.; Kuriki, K.; Kobayashi, R.; Takabayashi, N.; Furukawa, K.; Kosukegawa, M.; Nakajima, H.; Hara, K. Giant intrahepatic biliary cystadenoma in a male: A case report, immunohistopathological analysis, and review of the literature. Dig. Dis. Sci., 2005, 50, 1384-1389.
[8]
Karak, P.K.; Karak, A.K.; Singh, S.P.; Mukaopadhyay, S.; Berry, M. Biliary cystadenoma mistaken as hydatid cyst. Trop. Gastroenterol., 1993, 14, 109-113.
[9]
Seo, J.K.; Kim, S.H.; Lee, S.H.; Park, J.K.; Woo, S.M.; Jeong, J.B.; Hwang, J.H.; Ryu, J.K.; Kim, J.W.; Jeong, S.H.; Kim, Y.T.; Yoon, Y.B.; Lee, K.U.; Kim, S.H.; Kim, M.A. Appropriate diagnosis of biliary cystic tumors: Comparison with atypical hepatic simple cysts. Eur. J. Gastroenterol. Hepatol., 2010, 22, 989-996.
[10]
Ratti, F.; Ferla, F.; Paganelli, M.; Cipriani, F.; Aldrighetti, L.; Ferla, G. Biliary cystadenoma: short- and long-term outcome after radical hepatic resection. Updates Surg., 2012, 64, 13-18.
[11]
Federle, M.P.; Filly, R.A.; Moss, A.A. Cystic hepatic neoplasms: complementary roles of CT and sonography. AJR Am. J. Roentgenol., 1981, 136, 345-348.
[12]
Vuillemin-Bodaghi, V.; Zins, M.; Vullierme, M.P.; Denys, A.; Sibert, A.; Vilgrain, V.; Belghiti, J.; Menu, Y. Imaging of atypical cysts of the liver. Study of 26 surgically treated cases. Gastroenterol. Clin. Biol., 1997, 21, 394-399.
[13]
Lewin, M.; Mourra, N.; Honigman, I.; Fléjou, J.F.; Parc, R.; Arrivé, L.; Tubiana, J.M. Assessment of MRI and MRCP in diagnosis of biliary cystadenoma and cystadenocarcinoma. Eur. Radiol., 2006, 16, 407-413.
[14]
Lee, J.H.; Chen, D.R.; Pang, S.C.; Lai, Y.S. Mucinous biliary cystadenoma with mesenchymal stroma: Expressions of CA 19-9 and carcinoembryonic antigen in serum and cystic fluid. J. Gastroenterol., 1996, 31, 732-736.
[15]
Thomas, J.A.; Scriven, M.W.; Puntis, M.C.; Jasani, B.; Williams, G.T. Elevated serum CA 19-9 levels in hepatobiliary cystadenoma with mesenchymal stroma. Two case reports with immunohistochemical confirmation. Cancer, 1992, 70, 1841-1846.
[16]
Schoonbroodt, D.; Horsmans, Y.; Gigot, J.F.; Rahier, J.; Geubel, A.P. Biliary cystadenoma of the liver with elevated CA 19-9. Liver, 1994, 14, 320-322.
[17]
Sanchez, H.; Gagner, M.; Rossi, R.L.; Jenkins, R.L.; Lewis, W.D.; Munson, J.L.; Braasch, J.W. Surgical management of nonparasitic cystic liver disease. Am. J. Surg., 1991, 161, 113-118. discussion 8-9.
[18]
Thomas, K.T.; Welch, D.; Trueblood, A.; Sulur, P.; Wise, P.; Gorden, D.L.; Chari, R.S.; Wright, J.K. Jr.; Washington, K.; Pinson, C.W. Effective treatment of biliary cystadenoma. Ann. Surg., 2005, 241, 769-773. discussion 73-75.

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