摘要
背景：种族/少数民族患阿尔茨海默病和痴呆症的风险最高，但在临床研究中仍然不足。 目的：综合目前关于招募和保留阿尔茨海默病和痴呆症临床研究中种族/少数民族的策略的证据。 方法：我们通过搜索CINAHL，EMBASE，MEDLINE，PsycINFO和Scopus进行了系统评价。我们纳入了符合四项标准的研究；（1）包括种族/少数民族（非裔美国人，拉丁裔，亚洲人，美洲印第安人或阿拉斯加原住民，夏威夷原住民或其他太平洋岛民）; （2）实施阿尔茨海默病或痴呆临床研究的招募或保留策略; （3）在美国境内进行; （4）在同行评审期刊上发表。 结果：在19项纳入研究中，14项（73.7％）实施了招募策略，5项（26.3％）实施了招募和保留策略。 15项研究（78.9％）主要针对非洲裔美国人，2项（10.6％）针对非洲裔美国人和拉美裔人，2项（10.5％）针对亚洲人。所有文章在研究质量上都被评为弱。为招聘战略确定了四个主要主题：社区外展（94.7％），广告（57.9％），与医疗服务提供者的合作（42.1％）和转诊（21.1％）。确定了保留策略的三个主要主题：后续沟通（15.8％），维持社区关系（15.8％）和便利（10.5％）。 结论：我们的研究结果突出了一些有前途的招募和保留策略，研究人员在分配有限资源时应该优先考虑，但是，需要进行额外的精心设计的研究。通过在阿尔茨海默病和痴呆症研究中招募和保留更多的种族/少数民族，研究者可以更好地了解边缘化群体中疾病进展的异质性。 PROSPERO注册＃CRD42018081979。
关键词: 阿尔茨海默病，痴呆症，种族，少数民族，种族，招募，保留，系统评价。
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