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Current Psychiatry Research and Reviews

Editor-in-Chief

ISSN (Print): 2666-0822
ISSN (Online): 2666-0830

Review Article

A Developmental Psychopathology Perspective of Obsessive-Compulsive Disorder

Author(s): Michael R. Capawana*

Volume 15, Issue 2, 2019

Page: [105 - 115] Pages: 11

DOI: 10.2174/1573400515666190314162612

Price: $65

Abstract

Objective: This integrative review explores Obsessive-Compulsive Disorder (OCD) from the perspective of developmental psychopathology, in terms of its multifaceted etiology and course.

Background: Individuals affected by OCD experience intrusive and undesired thoughts accompanied by behaviors used to mitigate the unwanted images. Accordingly, there are several sub-types and personality dispositions reflective of the overall continuum of OCD, spanning normality and psychopathology. The etiology is complex, with generalized psychological and biological vulnerabilities, as well as contributors from life stress. Moreover, OCD is a disorder with a highly comorbid and overlapping presence; therefore, difficulties may arise when differentiating between OCD and other problems.

Conclusion: Treatment non-responsiveness is a pervasive trend in persons afflicted with OCD, but the most effective approach likely involves a stepped-care model incorporating cognitive-behavioral psychotherapy and psychotropic medications. Other considerations will also be discussed.

Keywords: Developmental psychopathology, OCD comorbidity, OCD etiology, cultural considerations, organismicdevelopmental approach, psychotropic medications.

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Graphical Abstract

[1]
McKay D, Taylor S, Abramowitz JS. Obsessive-compulsive disorder. In: McKay D, Abramowitz JS, Taylor S, Eds. Cognitive-behavior therapy: Turning failure into success. Washington, DC: American Psychological Association 2010; pp. 89-110.
[2]
American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington: American Psychiatric Association 2013.
[3]
Wheaton MG, Pinto A. Personality pathology in OCD comorbidity and contrast with OCPD and other personality disorders. In: Pittenger C, Ed. Obsessive-compulsive disorder: Phenomenology, pathophysiology, and treatment. New York: Oxford University Press 2017; pp. 655-66.
[4]
Barlow DH. Durand VM Abnormal Behavior. 4th ed. Belmont: Wadsworth 2005.
[5]
Nydegger R, Paludi M. Obsessive-compulsive disorder: Diagnostic, treatment, gender, and cultural issues. In: Plante TG, Ed. Mental disorders of the new millennium. 3rd ed. Westport: Praeger 2006; pp. 107-33.
[6]
Abramowitz JS. Obsessive-compulsive disorder. In: Craighead WE, Miklowitz DJ, Craighead LW, Eds. Psychopathology: History, diagnosis, and empirical foundations. New Jersey: John Wiley & Sons, Inc. 2008.
[7]
Leckman JF, Bloch MH. A developmental and evolutionary perspective on obsessive-compulsive disorder: Whence and whither compulsive hoarding? AM J Psychiatry 2008; 165(10): 1229-33.
[8]
Nestadt G, Di CZ, Riddle MA, et al. Obsessive-compulsive disorder: Subclassification based on co-morbidity. Psychol Med 2009; 39: 1491-501.
[9]
Storch EA, McKay D. Introduction to the special issue: Recent developments in childhood obsessive compulsive disorder. Child Youth Care Forum 2010; 39: 69-71.
[10]
Rutter M, Sroufe LA. Developmental psychopathology: Concepts and challenges. Dev Psychopathol 2000; 12: 265-96.
[11]
Sameroff AJ. Developmental systems and psychopathology. Dev Psychopathol 2000; 12: 297-312.
[12]
Mrdjenovich AJ, Bischof GH. Obsessive-compulsive complaints and academic performance in college students. College Student J 2003; 37: 145-56.
[13]
Frost RO. Cognitive approaches to obsessions and compulsions: Theory, assessment, and treatment. Amsterdam: Pergamon/Elsevier Science 2002.
[14]
Rubenstein CS, Peynircioglu ZF, Chambless DL, Pigott TA. Memory in sub-clinical obsessive-compulsive checkers. Behav Res Ther 1993; 31: 759-65.
[15]
Van Der Wee N, Ramsey NF, Van Megen H, Denys D, Westenberg H, Kahn RS. Spatial working memory in obsessive-compulsive disorder improves with clinical response: A functional MRI study. Eur Neuro-Psychopharmacology 2007; 17: 16-23.
[16]
Mataix-Cols D, Vallejo J, Sanchez-Turet M. The cut-off point in sub-clinical obsessive-compulsive research. Behav Cog Psychother 2000; 28: 225-33.
[17]
Rice KG, Pence SL. Perfectionism and obsessive-compulsive symptoms. J Psychopathol Behav Assess 2006; 28: 103-11.
[18]
Chamorro-Premuzic T. Creativity versus conscientiousness: Which is a better predictor of student performance? Appl Cog Psych 2006; 20: 521-31.
[19]
Mike A, King H, Oltmanns TF, Jackson JJ. Obsessive, compulsive, and conscientious? The relationship between OCPD and personality traits. J Pers 2018; 86(6): 952-72.
[20]
Cicchetti D, Sroufe LA. The past as prologue to the future: The times, they’ve been a-changin. Dev Psychopathol 2000; 12(3): 255-64.
[21]
Simonds LM, Thorpe SJ. Attitudes toward obsessive-compulsive disorders: An experimental investigation. Soc Psychiatry Psychiatr Epidemiol 2003; 38: 331-6.
[22]
Lewin AB, Storch EA, Geffken GR, Goodman WK, Murphy TKA. A neuropsychiatric review of pediatric obsessive-compulsive disorder: Etiology and efficacious treatments. Neuropsychiatric Dis Treat 2006; 2(1): 21-31.
[23]
U.S. Department of Health and Human Services. Mental Health: A report of the surgeon general. Washington, DC: U.S. Public Health Service 1999.
[24]
Matthews L, Reynolds S, Derisley J. Examining cognitive models of obsessive-compulsive disorder in adolescents. Behav Cog Psychother 2006; 35: 149-63.
[25]
Markarian Y, Larson MJ, Aldea MA, et al. Multiple pathways to functional impairment in obsessive-compulsive disorder. Clin Psych Rev 2010; 30: 78-88.
[26]
Leckman JF, Denys D, Simpson HB, et al. Obsessive-compulsive disorder: A review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM-V. Depress Anxiety 2010; 27(6): 507-27.
[27]
Bogetto F, Venturello S, Albert U, Maina G, Ravizza L. Gender-related clinical differences in obsessive-compulsive disorder. Eur Psychiatry 1999; 14(8): 434-41.
[28]
Fontenelle L, Marques C, Versiani M. The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder. Revista Brasileira de Psiquiatria 2002; 24(1): 7-11.
[29]
Lochner C, Hemmings SMJ, Kinnear CJ, et al. Gender in obsessive-compulsive disorder: Clinical and genetic findings. Eur Neuropsychopharm 2004; 14(2): 105-13.
[30]
Labad J, Mencho JM, Alonso P, et al. Gender differences in obsessive-compulsive symptom dimensions. Depress Anxiety 2008; 25(10): 832-8.
[31]
Pirurinsky S, Rosmarin DH, Pargament KI. Community attitudes towards culture-influenced mental illness: Scrupulosity vs. nonreligious OCD among Orthodox Jews. J Community Psychol 2009; 37(8): 949-58.
[32]
Dulaney S, Fiske AP. Cultural rituals and obsessive-compulsive disorder: Is there a common psychological mechanism? Ethos 1994; 22(3): 243-83.
[33]
Kyrios M, Sanavio E, Bhar S, Liguori L. Associations between obsessive-compulsive phenomena, affect, and beliefs: Cross-cultural comparisons of Australian and Italian data. Behav Cog Psychother 2001; 29: 409-22.
[34]
Yorulmaz O, Gencoz T, Woody S. Vulnerability factors in OCD symptoms: Cross-cultural comparisons between Turkish and Canadian samples. Clin Psychol Psychother 2010; 17(2): 110-21.
[35]
Wetterneck CT, Little TE, Rinehart KL, Cervantes ME, Hyde E, Williams M. Latinos with obsessive-compulsive disorder: Mental healthcare utilization and inclusion in clinical trials. J Obsessive Compuls Rel Disord 2012; 1: 85-97.
[36]
Abramowitz JS, Foa EB. Does comorbid major depressive disorder influence outcome of exposure and response prevention for OCD? Behav Ther 2000; 31: 795-800.
[37]
Bhar SS, Kyrios M. Cognitive personality styles associated with depressive and obsessive compulsive phenomena in a non-clinical sample. Behav Cog Psychother 1999; 27: 329-43.
[38]
Nestadt G, Samuels J, Riddle MA, et al. The relationship between obsessive-compulsive disorder and anxiety and affective disorders: Results from the Johns Hopkins OCD Family Study. Psychol Med 2001; 31: 481-7.
[39]
Kobori O, Sato H, Katsukura R, Harada S. Cognitive behavioural therapy for obsessive compulsive symptoms affected by past psychotic experience of schizophrenia: A case report. Behav Cog Psychother 2008; 36: 365-9.
[40]
Storch EA, Lewin AB, Geffken GR, Morgan JR, Murphy TK. The role of comorbid disruptive behavior in the clinical expression of pediatric obsessive-compulsive disorder. Behav Res Ther 2010; 48(12): 1204-10.
[41]
Alexander GM, Peterson BS. Testing the prenatal hormone hypothesis of tic-related disorders: Gender identity and gender role behavior. Dev Psychopathol 2004; 16: 407-20.
[42]
Medeiros GC, Grant JE. Gambling disorder and obsessive-compulsive personality disorder: A frequent but understudied comorbidity. J Behav Addiction 2018; 7(2): 366-74.
[43]
Abramowitz JS, Deacon BJ. Obsessive-compulsive disorder: Essential phenomenology and overlap with anxiety disorders. In: Abramowitz JS, Houts AC, Eds. Concepts and controversies in obsessive-compulsive disorder. New York: Springer 2005; pp. 119-35.
[44]
Peterson BS, Pine DS, Cohen P, Brook JS. Prospective, longitudinal study of tic, obsessive-compulsive, and attention-deficit/ hyperactivity disorders in an epidemiological sample. J Am Acad Child Adolesc Psychiatry 2001; 40(6): 685-95.
[45]
Rapoport J. Obsessive compulsive disorder and basil ganglia dysfunction. Psychol Med 1990; 20: 465-9.
[46]
Camarena B, Rinetti G, Cruz C, Hernandez S, de la Fuente JR, Nicolini H. Association study of the serotonin transporter gene polymorphism in obsessive-compulsive disorder. Int J Neuropsychopharmacology 2001; 4: 269-72.
[47]
Boedhoe PSW, Schmaal L, Abe Y, et al. Distinct subcortical volume alterations in pediatric and adult OCD: A worldwide meta and mega analysis. Am J Psychiatry 2017; 174(1): 60-9.
[48]
McKay D, Abramovitch A, Abramowitz JS, Deacon B. Association and causation in brain imaging: The case of OCD. Am J Psychiatry 2017; 174(6): 597.
[49]
Maia TV, Cooney RE, Peterson BS. The neural bases of obsessive-compulsive disorder in children and adults. Dev Psychopathol 2008; 20: 1251-83.
[50]
Velayudhan L, Katz AW. Late-onset obsessive-compulsive disorder: The role of stressful life events. Int Psychogeriatr 2006; 18(2): 341-4.
[51]
Rasgon A, Lee WH, Leibu E, et al. Neural correlates of affective and non-affective cognition in obsessive compulsive disorder: A meta-analysis of functional imaging studies. Eur Psychiatry 2017; 46: 25-32.
[52]
Ameis SH, Lerch JP, Taylor MJ, et al. A diffusion tensor imaging study in children with ADHD, autism spectrum disorder, OCD, and matched controls: Distinct and non-distinct white matter disruption and dimensional brain-behavior relationships. Am J Psychiatry 2016; 173(12): 1213-22.
[53]
Nicolini H, Arnold P, Nestadt G, Lanzagorta N, Kennedy JL. Overview of genetics and obsessive-compulsive disorder. Psychiatry Res 2009; 170: 7-14.
[54]
Taylor S. Molecular genetics of obsessive-compulsive disorder: A comprehensive meta-analysis of genetic association studies. Molecular Psych 2013; 18(7): 799-805.
[55]
Khramtsova EA, Heldman R, Derks EM, Yu D, Davis LK, Stranger BE. Sex differences in the genetic architecture of obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet 2018. [Epub ahead of print].
[56]
Zilhão NR, Smit DJ, Boomsma DI, Cath DC. Cross-disorder genetic analysis of tic disorders, obsessive-compulsive, and hoarding symptoms. Front Psych 2016; 7: 120.
[57]
Abramowitz JS, Khandker M, Nelson CA, Deacon BJ, Rygwall R. The role of cognitive factors in the pathogenesis of obsessive-compulsive symptoms: A prospective study. Behav Res Ther 2006; 44(9): 1361-74.
[58]
Vogel PA, Stiles TC, Nordahl HM. Cognitive personality styles in OCD outpatients compared to depressed outpatients and healthy controls. Behav Cog Psychother 2000; 28: 247-58.
[59]
Taylor S, Coles ME, Abramowitz JS, et al. How are dysfunctional beliefs related to obsessive-compulsive symptoms? J Cog Psychotherapy 2010; 24(3): 165-76.
[60]
Taylor S, Abramowitz JS, McKay D, et al. Do dysfunctional beliefs play a role in all types of obsessive-compulsive disorder? J Anxiety Disord 2006; 20(1): 85-97.
[61]
Burdick KE, Robinson DG, Malhotra AK, Szeszko PR. Neurocognitive profile analysis in obsessive-compulsive disorder. J Int Neuropsych Soc 2008; 14: 640-5.
[62]
Grisham JR, Fullana MA, Mataix-Cols D, Moffitt TE, Caspi A, Poulton R. Risk factors prospectively associated with adult obsessive-compulsive symptom dimensions and obsessive-compulsive disorder. Psychol Med 2011; 41: 2495-506.
[63]
Storch EA, Heidgerken AD, Adkins JW, Cole M, Murphy TK, Geffken GR. Peer victimization and the development of obsessive-compulsive disorder in adolescence. Depress Anxiety 2005; 21(1): 41-4.
[64]
Hinshaw SP, Cicchetti D. Stigma and mental disorder: Conceptions of illness, public attitudes, personal disclosure, and social policy. Dev Psychopathol 2000; 12: 555-98.
[65]
Timpano KR, Abramowitz JS, Mahaffey BL, Mitchell MA, Schmidt NB. Efficacy of a prevention program for postpartum obsessive-compulsive symptoms. J Psychiatr Res 2011; 45(11): 1511-7.
[66]
National Institute for Health and Care Excellence. Obsessive-compulsive disorder and body dysmorphic disorder: treatment 2005 [Accessed at: 2-1-2017]. Available at: https://www.nice. org.uk/guidance/CG31?UNLID=95916470201585103117
[67]
Strauss AY, Huppert JD, Simpson HB, Foa EB. What matters more? Common or specific factors in cognitive behavioral therapy for OCD: Therapeutic alliance and expectations as predictors of treatment outcome. Behav Res Ther 2018; 105: 43-51.
[68]
Abramowitz JS, Blakey SM, Reuman L, Buchholz JL. New directions in the cognitive behavioral treatment of OCD: Theory, research, and practice. Behav Ther 2018; 49(3): 311-22.
[69]
Hill NR, Beamish PM. Treatment outcomes for obsessive-compulsive disorder: A critical review. J Counsel Dev 2007; 85: 504-10.
[70]
Ovrehus EH, Martinsen AS, Hagen K, Hansen B, Kvale G. Prevalence of personality disorders in patients with OCD and relationship to treatment outcome. Clin Neuropsychiatry J Treat Eval 2016; 13(6): 130-5.
[71]
Pallanti S, Hollander E, Bienstock C, et al. Treatment non-response in OCD: Methodological issues and operational definitions. Int J Neuropsychopharm 2002; 5: 181-91.

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