Abstract
The number of publications that describe the development of novel molecular imprinted polymers (MIPs) has risen dramatically in recent years, demonstrating clearly the potential of this molecular recognition driven technique in a variety of separation-based and alternative technologies. This review covers the development of molecular imprinted polymers that have utilised biologically active substrates - in particular steroidal systems, as templates and then details the range of applications of these imprinted resins. The optimisation of molecular imprinting techniques for substrates of this type are described, starting from studies derived from early immunological theories, and concluding with coverage of state-of-the-art methods that are directed towards the next generation of MIPs
Keywords: steroidal, molecular imprinting, cholesterol, corticosterone, cortisol, testosterone, castasterone, molecular imprinted polymers, naproxen
Current Organic Chemistry
Title: Molecular Imprinting of Biologically Active Steroidal Systems
Volume: 6 Issue: 3
Author(s): L. Davidson and W. Hayes
Affiliation:
Keywords: steroidal, molecular imprinting, cholesterol, corticosterone, cortisol, testosterone, castasterone, molecular imprinted polymers, naproxen
Abstract: The number of publications that describe the development of novel molecular imprinted polymers (MIPs) has risen dramatically in recent years, demonstrating clearly the potential of this molecular recognition driven technique in a variety of separation-based and alternative technologies. This review covers the development of molecular imprinted polymers that have utilised biologically active substrates - in particular steroidal systems, as templates and then details the range of applications of these imprinted resins. The optimisation of molecular imprinting techniques for substrates of this type are described, starting from studies derived from early immunological theories, and concluding with coverage of state-of-the-art methods that are directed towards the next generation of MIPs
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Cite this article as:
Davidson L. and Hayes W., Molecular Imprinting of Biologically Active Steroidal Systems, Current Organic Chemistry 2002; 6 (3) . https://dx.doi.org/10.2174/1385272024605041
DOI https://dx.doi.org/10.2174/1385272024605041 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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