Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

K2CO3 Promoted Cascade Reaction for the Preparation of 1H-Imidazol-4- yl-1-amine Derivatives

Author(s): Wei Xu, Hao Yao, Xing Zhang, Changjiang Peng, Ling Li, Yuanyuan Zhang, Shan Qian, Lingling Yang* and Zhouyu Wang*

Volume 17, Issue 2, 2020

Page: [127 - 132] Pages: 6

DOI: 10.2174/1570178616666190226144620

Price: $65

Abstract

A K2CO3 promoted efficient one pot two-step method for the preparation of 1H-imidazol-4- yl-1-amine derivatives has been developed. A series of second amines with an imidazole group were obtained with 56%-91% yields by the K2CO3 promoted amination of acetates and nitrogen deprotection of the imidazole process.

Keywords: One pot, second amine, imidazole, nucleophilic displacement, K2CO3, amination.

Graphical Abstract

[1]
Armer, R.; Bingham, M.; Pesnot, T.; Cignoux, C. PCT Int. Appl. WO 2016051181,. 2016.
[2]
Fan, Y.L.; Jin, X.H.; Huang, Z.P.; Yu, H.F.; Zeng, Z.G.; Gao, T.; Feng, L.S. Eur. J. Med. Chem., 2018, 150, 347-365.
[3]
Guido, G.; Henri, S.; Annick, G.; Marius, H.C.; Roger, D.N. Bioorg. Med. Chem. Lett., 2012, 22, 5244-5248.
[4]
Anil, V.; Yimin, Q.; Andreas, V.; Michelle, A. B.; Junko, O.; Said, M. S.; Andrew D., H. J. Med. Chem., 1999, 42, 1333-1340.
[5]
Bureš, F.; Kulhánek, J. Tetrahedron Asymmetry, 2005, 16, 1347-1354.
[6]
Baxter, E.W.; Reitz, A.B. Org. React; Wiley, 2002, p. 1.
[7]
Birtill, J.J.; Chamberlain, M. Hall. J.; Wilson, R.; Costello, I. In: Catalysis of Organic Reactions; Herkers, F.E., Ed.; Dekker: New York, USA, 1998; pp. 255-271.
[8]
Ohkuma, T.; Noyori, R. In Comprehensive Asymmetric Catalysis; Jacobsen, E.N.; Pfaltz, A.; Yamamoto, H., Eds.; Springer: New York, USA, 2004, 1, pp. 199-222.
[9]
Nugent, T.C.; El-Shazly, M. Adv. Synth. Catal., 2010, 352, 753-819.
[10]
Fu, B.; Li, N.; Liang, X.M.; Dong, Y.H.; Wang, D.Q. Chinese J. Org. Chem, 2015, 27, 1-4.
[11]
Dixon, D.D.; Grina, J.; Josey, J.A.; Rizzi, J.P.; Schlachter, S.T.; Wallace, E.M.; Wang, B.; Wehn, P.; Yang, H. PCT Int. Appl., WO 2015175845, 2015.
[12]
Zhang, D.Y.; Zhang, R.H.; Zhong, B.Y.; Shi, C. PCT Int. Appl., WO 2014000418, 2014.
[13]
Hughes, G. OShea, P.; Goll, J.; Gauvreau, D.; Steele, J. Tetrahedron, 2009, 65, 3189-3196.
[14]
Ismaiel, A.M.; Gad, L.M.; Ghareib, S.A.; Bamanie, F.H. Moustafa. M.A. Med. Chem. Res., 2009, 18, 745-757.
[15]
Yang, L.L.; Ma, X.B.; Yuan, C.; He, Y.Y.; Li, L.; Fang, S.; Xia, W.; He, T.; Qian, S.; Xu, Z.H.; Li, G.B.; Wang, Z.Y. Eur. J. Med. Chem., 2017, 134, 230-241.
[16]
Yang, L.L.; He, Y.Y.; Chen, Q.L.; Qian, S.; Wang, Z.Y. J. Heterocycl. Chem., 2016, 54, 1457-1466.
[17]
Qian, S.; He, T.; Wang, W.; He, Y.Y.; Zhang, M.; Yang, L.L.; Li, G.B.; Wang, Z.Y. Bioorg. Med. Chem., 2016, 24, 6194-6205.
[18]
Qian, S.; Zhang, M.; He, Y.; Wang, W.; Liu, S. Future Med. Chem., 2016, 8, 1239-1258.
[19]
Evans, P.; Grange, R.; Clizbe, E. Synthesis, 2016, 48, 2911-2968.
[20]
You, S.L.; Zhu, X.Z.; Luo, Y.M.; Hou, X.L.; Dai, L.X. J. Am. Chem. Soc., 2001, 123, 7471-7472.
[21]
Detz, R.J.; Delville, M.M.; Hiemstra, H.; Maarseveen, J.H. Angew. Chem. Int. Ed., 2008, 47, 3837-3840.
[22]
Trost, B.M.; Zhang, T.; Sieber, J.D. Chem. Sci., 2010, 1, 427-440.
[23]
Chen, J.P.; Peng, Q.; Lei, B.L.; Hou, X.L.; Wu, Y.D. J. Am. Chem. Soc., 2011, 133, 14180-14183.
[24]
Ye, K.Y.; He, H.; Liu, W.B.; Dai, L.X.; Helmchen, G.; You, S.L. J. Am. Chem. Soc., 2011, 133, 19006-19014.
[25]
Arnold, J.S.; Nguyen, H.M. J. Am. Chem. Soc., 2012, 134, 8380-8383.
[26]
Arnold, J.S.; Mwenda, E.T.; Nguyen, H.M. Angew. Chem. Int. Ed., 2014, 53, 3688-3692.
[27]
Kawatsura, M.; Uchida, K.; Terasaki, S.; Tsuji, H.; Minakawa, M.; Itoh, T. Org. Lett., 2014, 16, 1470-1473.
[28]
Wang, X.; Guo, P.; Han, Z.; Wang, X.; Wang, Z.; Ding, K. J. Am. Chem. Soc., 2014, 136, 405-411.
[29]
Wu, H.; Xie, F.; Wang, Y.; Zhao, X.; Liu, D.; Zhang, W. Org. Biomol. Chem., 2015, 13, 4248-4254.
[30]
Cai, A.; Guo, W.; Martinez-Rodriguez, L.; Kleij, A.W. J. Am. Chem. Soc., 2016, 138, 14194-14197.
[31]
Huo, X.; He, R.; Fu, J.; Zhang, J.; Yang, G.; Zhang, W. J. Am. Chem. Soc., 2017, 139, 9819-9822.
[32]
Jing, J.; Huo, X.; Shen, J.; Fu, J.; Meng, Q.; Zhang, W. Chem. Commun., 2017, 53, 5151-5154.
[33]
Wang, Y.N.; Wang, B.C.; Zhang, M.M.; Gao, X.W.; Li, T.R.; Lu, L.Q.; Xiao, W.J. Org. Lett., 2017, 19, 4094-4097.
[34]
Xia, C.; Shen, J.; Liu, D.; Zhang, W. Org. Lett., 2017, 19, 4251-4254.
[35]
Zhou, Y.; Breit, B. Chemistry, 2017, 23, 18156-18160.
[36]
Huo, X. Zhang, J.; Fu, J.; He, R.; Zhang, W. J. Am. Chem. Soc., 2018, 140, 2080-2084.
[37]
Jiang, X.; Boehm, P.; Hartwig, J.F. J. Am. Chem. Soc., 2018, 140, 1239-1242.
[38]
Reddy, K.H.V.; Bédier, M.; Bouzbouz, S. Eur. J. Org. Chem., 2018, 1455-1459.

Rights & Permissions Print Cite
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version552msRequest Duration28MBMemory UsageGET article/{article_id}/{param?}Route
  • warninglog[20:14:45] LOG.warning: Optional parameter $article_id declared before required parameter $request i...
  • warninglog[20:14:45] LOG.warning: trim(): Passing null to parameter #1 ($string) of type string is deprecated ...
  • warninglog[20:14:45] LOG.warning: Function strftime() is deprecated in /home/alphaeurekaselec/public_html/stor...
  • Booting (236ms)time
  • Application (315ms)time
  • 1 x Application (57.13%)
    315ms
    1 x Booting (42.86%)
    236ms
    14 templates were rendered
    • articlearticle.blade.php#?blade
    • includes.article_top_bannerarticle_top_banner.blade.php#?blade
    • includes.article_referencearticle_reference.blade.php#?blade
    • export_citation_formexport_citation_form.blade.php#?blade
    • includes.article_bottom_bannerarticle_bottom_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • includes.journal_rightmenujournal_rightmenu.blade.php#?blade
    • includes.journal_right_bannerjournal_right_banner.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET article/{article_id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ArticleController@GetArticleDetails
    namespace
    App\Http\Controllers
    where
    as
    article
    file
    app/Http/Controllers/ArticleController.php:1974-2510
    36 statements were executed, 4 of which were duplicates, 32 unique. Show only duplicated204ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('221967817','',1,1740773685,1740773685) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1740773685
      3.63msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('221967817','/article/96867',1,1740773685,1740773685)
      250μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 221967817 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 221967817) limit 1
      20.66msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 221967817
      • 1: 221967817
      • 2: 221967817
      • 3: 221967817
      • 4: 221967817
      • 5: 221967817
      • 6: 221967817
      • 7: 221967817
      • 8: 221967817
      • 9: 221967817
      • 10: 221967817
      • 11: 221967817
      • 12: 221967817
      • 13: 221967817
      • 14: 221967817
      • 15: 221967817
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • SELECT at.type_name, p.copyright, p.publisher_location,m.month,y.year, a.publish_on, a.nid article_nid,a.article_id, a.pmid, a.issue_id, a.title, a.abstract,a.podcast,a.altmetric_score,a.altmetric_url,a.kudos_url, a.page_count, a.first_page, a.elocator, a.last_page, i.publication_date, a.file_name, a.file_path, a.doi, a.is_epub,a.epub_type, a.volume_id, a.is_uploaded, a.editor_choice, a.is_epub, j.image_file_name, a.article_no, a.art_type AS article_type, a.supplementary_filename,a.html_filename,a.prc_filename,a.epub_filename, a.graph_abs_lg_filename, a.graph_abs_sm_filename, a.oa_image_lg_filename, a.oa_image_sm_filename, j.journal_banner,a.animated_abstract,a.erratum_in,a.erratum_for, (CASE WHEN a.issue_id =0 THEN j.epub_price ELSE j.price END) AS sell_price, j.epub_price, j.nid AS jour_nid, j.title AS journal_title, j.issn, j.eissn,j.journal_id, j.subtitle AS jour_subtitle, v.volume_id,v.volume_name AS volume, v.year_id, i.title AS issue, i.month_id ,i.type issue_type, j.subtitle,j.formerly_title, ac.subtitle AS epub_title,a.crossmark_enabled,a.text_mining_urls,a.license_urls,a.created, a.receivedate, a.revisedate, a.acceptdate,js.js_title FROM article a LEFT JOIN article_section ac ON a.is_epub = ac.art_sec_id LEFT JOIN journal_section js ON a.js_id = js.js_id LEFT JOIN article_type at ON a.art_type = at.art_type_id LEFT JOIN issue i ON a.issue_id = i.issue_id LEFT JOIN month m ON m.id = i.month_id LEFT JOIN volume v ON v.volume_id = a.volume_id INNER JOIN year y ON y.id = v.year_id INNER JOIN journal j ON j.journal_id = a.journal_id INNER JOIN publisher p ON p.publisher_id = j.publisher_id WHERE a.article_id=96867
      1.12msalphaeurekaselec_live_10_06_2022Article.php#408
      Backtrace
      • 11. app/Models/Article.php:408
      • 12. app/Http/Controllers/ArticleController.php:2515
      • 13. app/Http/Controllers/ArticleController.php:2035
      • 14. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 15. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `journal` where `journal_id` = 48 limit 1
      1.22msalphaeurekaselec_live_10_06_2022Journal.php#64
      Bindings
      • 0: 48
      Backtrace
      • 14. app/Models/Journal.php:64
      • 15. app/Http/Controllers/ArticleController.php:2516
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=48) and sj.journal_id!=48 group by `j`.`nid`) as `aggregate_table`
      850μsalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 16. app/Models/Subject.php:200
      • 17. app/Http/Controllers/ArticleController.php:2517
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=48) and sj.journal_id!=48 group by `j`.`nid` order by `j`.`journal_id` asc limit 10 offset 0
      740μsalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 14. app/Models/Subject.php:200
      • 15. app/Http/Controllers/ArticleController.php:2517
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=48) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid`) as `aggregate_table`
      1.14msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 16. app/Models/Subject.php:220
      • 17. app/Http/Controllers/ArticleController.php:2518
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=48) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid` order by `v`.`ebook_volume_id` desc limit 10 offset 0
      1.1msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 14. app/Models/Subject.php:220
      • 15. app/Http/Controllers/ArticleController.php:2518
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `keywords` where `article_id` = '96867'
      14.44msalphaeurekaselec_live_10_06_2022Keywords.php#43
      Bindings
      • 0: 96867
      Backtrace
      • 13. app/Models/Keywords.php:43
      • 14. app/Http/Controllers/ArticleController.php:2519
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `article_citation` where `article_id` = '96867'
      21.36msalphaeurekaselec_live_10_06_2022Article.php#1570
      Bindings
      • 0: 96867
      Backtrace
      • 13. app/Models/Article.php:1570
      • 14. app/Http/Controllers/ArticleController.php:2520
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`article_id` = '96867' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      10.86msalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 96867
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ArticleController.php:2533
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      390μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2535
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `subtitle` from `journal` where `continues_publication_journal` = 1
      740μsalphaeurekaselec_live_10_06_2022Article.php#1960
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/Article.php:1960
      • 14. app/Http/Controllers/ArticleController.php:2062
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 48 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
      51.26msalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/ArticleController.php:2068
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 1 and a.journal_id = 48 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      17.72msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2070
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 4 and a.journal_id = 48 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      16.66msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2071
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select pdf, html, epub, prc from `article_metrics` where `article_id` = 96867 limit 1
      4.24msalphaeurekaselec_live_10_06_2022Article.php#744
      Bindings
      • 0: 96867
      Backtrace
      • 14. app/Models/Article.php:744
      • 15. app/Http/Controllers/ArticleController.php:2091
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from content_by_diseases where content_id = 96867 and content_type = 'article' order by status desc limit 1
      430μsalphaeurekaselec_live_10_06_2022Article.php#751
      Backtrace
      • 11. app/Models/Article.php:751
      • 12. app/Http/Controllers/ArticleController.php:2094
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `node_meta` where `nid` = 170229 limit 1
      290μsalphaeurekaselec_live_10_06_2022Meta.php#30
      Bindings
      • 0: 170229
      Backtrace
      • 14. app/Models/Meta.php:30
      • 15. app/Http/Controllers/ArticleController.php:2101
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      330μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2108
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `tbl_ht_submission` as `h` where `h`.`subtitle` = 'LOC' and (h.proposal_closing_date = 0 OR TO_DAYS(FROM_UNIXTIME(h.proposal_closing_date)) >= TO_DAYS(NOW())) order by `h`.`manuscript` asc
      410μsalphaeurekaselec_live_10_06_2022Article.php#2025
      Bindings
      • 0: LOC
      Backtrace
      • 13. app/Models/Article.php:2025
      • 14. app/Http/Controllers/ArticleController.php:2112
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '96867' and content_type = 'a' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      520μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2186
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '9542' and content_type = 'i' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      460μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2207
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '2679' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      440μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2231
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2679) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2679) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2679)
      20.75msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2272
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 9542) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 9542) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 9542)
      890μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2297
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 96867) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 96867) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 221967817 and j.to_ip >=221967817 )) and ((j.from_date <= 1740773685 and j.to_date >= 1740773685 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 96867)
      810μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2329
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `first_page` < '127' and is_uploaded = 1 and issue_id = 9542 order by cast(first_page as SIGNED) desc limit 1
      930μsalphaeurekaselec_live_10_06_2022Article.php#1819
      Bindings
      • 0: 127
      Backtrace
      • 14. app/Models/Article.php:1819
      • 15. app/Http/Controllers/ArticleController.php:2470
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `last_page` > '132' and is_uploaded = 1 and issue_id = 9542 order by cast(first_page as SIGNED) asc limit 1
      730μsalphaeurekaselec_live_10_06_2022Article.php#1831
      Bindings
      • 0: 132
      Backtrace
      • 14. app/Models/Article.php:1831
      • 15. app/Http/Controllers/ArticleController.php:2472
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `language_id` from `multilanguage` where `short_code` = 'en'
      310μsalphaeurekaselec_live_10_06_2022ArticleController.php#2497
      Bindings
      • 0: en
      Backtrace
      • 14. app/Http/Controllers/ArticleController.php:2497
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select `source_lang_label`, `target_lang_label` from `multilanguage_labels` where `target_lang_id` = 1
      330μsalphaeurekaselec_live_10_06_2022MultiLanguage.php#23
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/MultiLanguage.php:23
      • 14. app/Http/Controllers/ArticleController.php:2498
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `id` from `multilanguage_article` where `article_id` = 96867 limit 1
      4.03msalphaeurekaselec_live_10_06_2022ArticleController.php#2506
      Bindings
      • 0: 96867
      Backtrace
      • 16. app/Http/Controllers/ArticleController.php:2506
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 48 and `b`.`banner_from_date` <= 1740773685 and `b`.`banner_to_date` >= 1740773685 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.69msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 48
      • 3: 1740773685
      • 4: 1740773685
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 48 and `b`.`banner_from_date` <= 1740773685 and `b`.`banner_to_date` >= 1740773685 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.63msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 48
      • 3: 1740773685
      • 4: 1740773685
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='5e24c478364199c94230433f64ae5529'
      340μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:291
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\MultiLanguage
    1MultiLanguage.php#?
        _token
        pfxnxqPrYOi2OXHBvcrxI3xwyhmWZvFXyz2rdHM5
        uc_cart_id
        5e24c478364199c94230433f64ae5529
        _previous
        array:1 [ "url" => "http://alpha.eurekaselect.com/article/96867" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /article/96867
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:9 [ "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6IkRvTDN1RWExQnFFTGdKTTdYTUJlaVE9PSIsInZhbHVlIjoidThlV0FKdXNSSHhvRlhLV0lmRnNJeWpqV0VpazdpWVMxT3ZyNEZ6YlNDdz0iLCJtYWMiOiJhZTJlYTIwNjg1MWI0NWYwNTM4YjAxYjgyNGRlODBmYzk1ZWU2NWRmYmIwN2MyMGZhNGQ2YTRmMTNjMjRlYjRlIiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6IkRvTDN1RWExQnFFTGdKTTdYTUJlaVE9PSIsInZhbHVlIjoidThlV0FKdXNSSHhvRlhLV0lmRnNJeWpqV0VpazdpWVMxT3ZyNEZ6YlNDdz0iLCJtYWMiOiJhZTJlYTIwNjg1MWI0" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "connection" => array:1 [ 0 => "keep-alive" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Fri, 28 Feb 2025 20:14:45 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IkoveWF0ajhEZExlRVJEUUJQT2VZRFE9PSIsInZhbHVlIjoiY2gxcitLNE9tazM4MWJ3ZC9uQWxtMUVreXhJY3NiWnZWV1lsMFpTSkpoejdnWVBTUHZkVXJrdU1FKzlUNzV5czcrcS9JdHBDUHZaRHVoL1JLOEJCZFNXNXMraGlEeFp6ekJBVTVmM0NxMURxRHdYbVlIbGhCNWVnT2lSMXJpOHoiLCJtYWMiOiJiMTRiMTAwNzJhMGJjZjVkYzMzZjRkZDNiNzcxMjEzNjZjMjE5MTUyMWM0M2ZjMGM0ZmFhYTgxM2NlNDMwY2RlIiwidGFnIjoiIn0%3D; expires=Mon, 03 Mar 2025 08:14:45 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6IkoveWF0ajhEZExlRVJEUUJQT2VZRFE9PSIsInZhbHVlIjoiY2gxcitLNE9tazM4MWJ3ZC9uQWxtMUVreXhJY3NiWnZWV1lsMFpTSkpoejdnWVBTUHZkVXJrdU1FKzlUNzV5czcrcS9Jd" 1 => "alphaeurekaselectnet_session=eyJpdiI6IlJyUjhCUHZjVDF0bko0MUdBbysyaXc9PSIsInZhbHVlIjoiM3JJclVwZFpHdG5GODdtSmoveTVSMDNWN1VINjlLazl0bzFLcnVmd2FKUGQ2SW9rQkVMbksvWFpFV0orcU1CUURqK1k5aytWdkxJMVg1RlZFTXJ2MlpjQmk1QlpXdnZ0d0x4RHFiTmxWbnk5eGwyY3JFVjF6RWN0NGpzRlJpVmYiLCJtYWMiOiJlNWFlYmQzOWEzM2UxMDlmMzk3YzlkNDRlYTA0ZDkyZGQ0YWZjMzkyOGU4ZDhiMDIxN2IwYTU2MjMxZDMyNTUxIiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6IlJyUjhCUHZjVDF0bko0MUdBbysyaXc9PSIsInZhbHVlIjoiM3JJclVwZFpHdG5GODdtSmoveTVSMDNWN1VINjlLazl0bzFLcnVmd2FKUGQ2SW9rQkVMbksvWFp" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IkoveWF0ajhEZExlRVJEUUJQT2VZRFE9PSIsInZhbHVlIjoiY2gxcitLNE9tazM4MWJ3ZC9uQWxtMUVreXhJY3NiWnZWV1lsMFpTSkpoejdnWVBTUHZkVXJrdU1FKzlUNzV5czcrcS9JdHBDUHZaRHVoL1JLOEJCZFNXNXMraGlEeFp6ekJBVTVmM0NxMURxRHdYbVlIbGhCNWVnT2lSMXJpOHoiLCJtYWMiOiJiMTRiMTAwNzJhMGJjZjVkYzMzZjRkZDNiNzcxMjEzNjZjMjE5MTUyMWM0M2ZjMGM0ZmFhYTgxM2NlNDMwY2RlIiwidGFnIjoiIn0%3D; expires=Mon, 03-Mar-2025 08:14:45 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6IkoveWF0ajhEZExlRVJEUUJQT2VZRFE9PSIsInZhbHVlIjoiY2gxcitLNE9tazM4MWJ3ZC9uQWxtMUVreXhJY3NiWnZWV1lsMFpTSkpoejdnWVBTUHZkVXJrdU1FKzlUNzV5czcrcS9Jd" 1 => "alphaeurekaselectnet_session=eyJpdiI6IlJyUjhCUHZjVDF0bko0MUdBbysyaXc9PSIsInZhbHVlIjoiM3JJclVwZFpHdG5GODdtSmoveTVSMDNWN1VINjlLazl0bzFLcnVmd2FKUGQ2SW9rQkVMbksvWFpFV0orcU1CUURqK1k5aytWdkxJMVg1RlZFTXJ2MlpjQmk1QlpXdnZ0d0x4RHFiTmxWbnk5eGwyY3JFVjF6RWN0NGpzRlJpVmYiLCJtYWMiOiJlNWFlYmQzOWEzM2UxMDlmMzk3YzlkNDRlYTA0ZDkyZGQ0YWZjMzkyOGU4ZDhiMDIxN2IwYTU2MjMxZDMyNTUxIiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6IlJyUjhCUHZjVDF0bko0MUdBbysyaXc9PSIsInZhbHVlIjoiM3JJclVwZFpHdG5GODdtSmoveTVSMDNWN1VINjlLazl0bzFLcnVmd2FKUGQ2SW9rQkVMbksvWFp" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "pfxnxqPrYOi2OXHBvcrxI3xwyhmWZvFXyz2rdHM5" "uc_cart_id" => "5e24c478364199c94230433f64ae5529" "_previous" => array:1 [ "url" => "http://alpha.eurekaselect.com/article/96867" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-28 20:14:45GET/article/96867314361