Abstract
The paper reviews basic aspects of the biology of Trypanosoma cruzi emphasizing the following topics: (a) developmental stages of the life cycle in the vertebrate and invertebrate hosts (b) the cytoskeleton of the protozoan, especially the sub-pellicular microtubules (c) the flagellum, emphasizing its attachment to the protozoan body through specialized junctions (d) the kinetoplast-mitochondrion complex, describing its structural organization and the replication of the kinetoplast-DNA (e) the peroxisome (glycosome) and its role in the metabolism of the cell (f) the acidocalcisome, describing its morphology, biochemistry and functional role (g) the cytostome and the endocytic pathway (h) the organization of the endoplasmic reticulum-Golgi complex (i) the nucleus, describing its structural organization during interphase and division, and (j) basic aspects of the process of interaction of the parasite with host cells.
Keywords: Trypanosoma cruzi, Rhodinus, prolixus, Triatoma infestans, Panstrongylus, megistus, Peroxisome, Glycosome, Trypanosomatids, Acidocalcisome
Current Pharmaceutical Design
Title: Basic Cell Biology of Trypanosoma cruzi
Volume: 8 Issue: 4
Author(s): Wanderley De. Souza
Affiliation:
Keywords: Trypanosoma cruzi, Rhodinus, prolixus, Triatoma infestans, Panstrongylus, megistus, Peroxisome, Glycosome, Trypanosomatids, Acidocalcisome
Abstract: The paper reviews basic aspects of the biology of Trypanosoma cruzi emphasizing the following topics: (a) developmental stages of the life cycle in the vertebrate and invertebrate hosts (b) the cytoskeleton of the protozoan, especially the sub-pellicular microtubules (c) the flagellum, emphasizing its attachment to the protozoan body through specialized junctions (d) the kinetoplast-mitochondrion complex, describing its structural organization and the replication of the kinetoplast-DNA (e) the peroxisome (glycosome) and its role in the metabolism of the cell (f) the acidocalcisome, describing its morphology, biochemistry and functional role (g) the cytostome and the endocytic pathway (h) the organization of the endoplasmic reticulum-Golgi complex (i) the nucleus, describing its structural organization during interphase and division, and (j) basic aspects of the process of interaction of the parasite with host cells.
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Cite this article as:
Souza De. Wanderley, Basic Cell Biology of Trypanosoma cruzi, Current Pharmaceutical Design 2002; 8 (4) . https://dx.doi.org/10.2174/1381612023396276
DOI https://dx.doi.org/10.2174/1381612023396276 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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