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Letters in Organic Chemistry

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ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

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Research Article

Efficient Synthesis of Novel Thioureidobenzamido Alkyl Naphthols in Molten Tetrabutylammonium Bromide

Author(s): Arman Shokooh Saljooghi, Hojatollah Khabazzadeh* and Moj Khaleghi

Volume 16, Issue 11, 2019

Page: [906 - 910] Pages: 5

DOI: 10.2174/1570178616666190123120127

Price: $65

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Abstract

A new series of benzamido alkyl naphthols were synthesized from the multi-component reaction of 4-(3′-methylthioureido)benzamide, aromatic aldehydes and 2-naphthol. Molten tetrabutyl ammonium bromide was used as a very efficient medium for this reaction while the use of common organic solvents gave no or poor yields. This method is an interesting instance of using molten salt as a medium in multicomponent reactions.

Keywords: Molten salt, 2-naphthol, thioureidobenzamide, 4-amino benzamide, tetrabutyl ammonium bromide, aronatic aldehydes.

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