摘要
金属在活生物体中扮演的角色已得到充分确立,并需要进行广泛的研究。其中一些参与电子交换反应。由于氧化应激,此类反应会导致自由基产生,从而对生物系统产生不利影响。由于“非生物”金属在现代文明中起着至关重要的作用,因此也值得一提。镧系元素(Ln)被广泛用于现代技术中。结果,人类对它们的暴露正在增加。它们具有许多已建立的医学应用,并且因其潜在的抗病毒,抗癌和抗炎特性而受到广泛研究。目前的审查集中在镧(La)及其对氧化应激的影响。镓(Ga)是另一种在现代高科技中广泛使用的金属。在某些方面,它显示出与La的某些相似之处,因此它也是本综述的主题。两种金属均表现出离子拟态,使其能够特异性靶向恶性细胞,引发细胞凋亡,从而使其简单的盐和配位复合物有望成为未来抗癌药物的候选物。
关键词: 镧,镓,氧化应激,抗氧化剂,抗癌剂,细胞凋亡。
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