N-Substituted Amides as Chiral Ligands for Catalytic Asymmetric Reactions

Title: N-Substituted Amides as Chiral Ligands for Catalytic Asymmetric Reactions

Volume: 6 Issue: 10

Author(s): Ji Zhang, Hai-Bing Zhou and Ru-Gang Xie

Affiliation:

Keywords: N-Substituted Amides, Chiral Ligands, squaramides

Abstract: In this review we introduced many kinds of bifunctional N-substituted amides, including phosphinamides and phosphoramides, squaramides, sulfonamides and so on which were applied to the asymmetric reactions. More emphasis were given to the asymmetric borane reduction of prochiral ketones, the reaction conditions and mechanisms were discussed systematically. At the same time, other reactions, including asymmetric addition, Diels-Alder reaction and Aldol reactions catalyzed by chiral N-substituted amides were also reviewed.

Cite this article as:

Zhang Ji, Zhou Hai-Bing and Xie Ru-Gang, N-Substituted Amides as Chiral Ligands for Catalytic Asymmetric Reactions, Current Organic Chemistry 2002; 6 (10) . https://dx.doi.org/10.2174/1385272023373806