Abstract
The chemical constituents produced by Chinese higher fungi, including thirty two basidiomycete and six ascomycete species, have been investigated in the past decades. A variety of new secondary metabolites associated with diverse structural types of terpenoids, steroids, sphingolipids, perylenequinones, p-terphenyls, pyranones, and heterocyclic compounds, which exhibited antitumor, anti-inflammatory, cytotoxic, enzyme inhibitory, antiviral, neuritogenic, antibiotic, and other activities, have been discovered. Recent progress in the structures and interesting biological properties of compounds isolated from these higher fungi is discussed in this review.
Keywords: Ganoderma lucidum, triterpene, ganodermanondiol, Bioassay-guided fractionation, sesquiterpenes, sphingolipids, phytopathogenic fungi, angiogenesis inhibitors
Current Organic Chemistry
Title: New Biologically Active Metabolites from Chinese Higher Fungi
Volume: 10 Issue: 8
Author(s): Gao Jin-Ming
Affiliation:
Keywords: Ganoderma lucidum, triterpene, ganodermanondiol, Bioassay-guided fractionation, sesquiterpenes, sphingolipids, phytopathogenic fungi, angiogenesis inhibitors
Abstract: The chemical constituents produced by Chinese higher fungi, including thirty two basidiomycete and six ascomycete species, have been investigated in the past decades. A variety of new secondary metabolites associated with diverse structural types of terpenoids, steroids, sphingolipids, perylenequinones, p-terphenyls, pyranones, and heterocyclic compounds, which exhibited antitumor, anti-inflammatory, cytotoxic, enzyme inhibitory, antiviral, neuritogenic, antibiotic, and other activities, have been discovered. Recent progress in the structures and interesting biological properties of compounds isolated from these higher fungi is discussed in this review.
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Cite this article as:
Jin-Ming Gao, New Biologically Active Metabolites from Chinese Higher Fungi, Current Organic Chemistry 2006; 10 (8) . https://dx.doi.org/10.2174/138527206776894393
DOI https://dx.doi.org/10.2174/138527206776894393 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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