Abstract
The Baylis-Hillman reaction is one of the most powerful carbon-carbon bond-forming methods in organic synthesis. The Baylis-Hillman adducts have been widely used as intermediates for the synthesis of useful acyclic compounds as well as many cyclic compounds including heterocyclic ones. In this review the synthetic applications of the Baylis-Hillman adducts toward cyclic compounds have been categorized according to the key reaction type.
Keywords: baylis-hillman, cyclic compound
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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