摘要
开发创新的药物输送系统，具有多种药物特性，具有更好的有效性和安全性，因此一直受到高度关注。壳聚糖是一种衍生自天然几丁质生物质的氨基多糖，作为新兴的药物赋形剂和药物递送实体之一，已经受到很多关注。脱乙酰壳多糖及其衍生物可用于直接压片，作为控制释放或改善溶出的崩解剂。据报道壳聚糖用于药物递送系统以产生具有增强的粘膜粘附性，渗透性，吸收性和生物利用度的药物。由于壳聚糖及其衍生物的成膜和离子性质，在水凝胶制剂中使用微球技术的药物释放机制与药物产品开发特别相关。该综述强调了壳聚糖在药物递送中的适用性和未来，特别注意药物加载和从壳聚糖基水凝胶中释放。对有利的无毒性，生物相容性，生物降解性，溶解性和分子量变化的广泛研究使得该聚合物成为开发新型药物递送系统的有吸引力的候选者，包括各种先进的治疗应用，例如基因递送，基于DNA的药物，器官特异性药物载体，癌症药物载体等
关键词: 生物聚合物，壳聚糖，药物递送，药物赋形剂，载药，药物载体水凝胶。
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