摘要
晚期糖基化终产物受体（RAGE）是一种重要的细胞表面受体，属于IGG超家族，目前被认为是一种模式识别受体。由于其在许多人类临床环境中的相关性，它现在被认为是一个非常有吸引力的治疗目标。然而，这种受体的特殊特征，如具有不同结合域的配体的广泛组合、许多RAGE变体的存在以及导致不同信号的细胞质适配器的存在，是寻找抑制RAGE信号的成功药理学方法的重要限制。因此，本综述旨在展示抑制RAGE信号的最有希望的方法，并提供这方面进展的最新综述。
关键词: 晚期糖基化终产物受体、晚期糖基化终产物、细胞内信号、拮抗剂、抑制剂、细胞质适配器。
图形摘要
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