摘要
自噬是一种保守的、受调控的细胞过程，用于降解异常蛋白质和破坏细胞器。文献报道自噬失调与糖尿病的发病过程密切相关，如胰腺β细胞功能受损、外周胰岛素抵抗、糖尿病并发症等。新出现的证据表明，天然产品可能通过调节自噬而具有抗糖尿病活性。本文综述了通过调节自噬作用而产生的针对糖尿病发病机制的天然产物，并强调了其可能的作用机制，为糖尿病的治疗提供了潜在的药物选择或治疗方法。
关键词: 自噬，糖尿病，胰岛素抵抗，天然产物，糖尿病并发症，发病机制。
图形摘要
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