腹主动脉瘤的炎症细胞和蛋白酶及其并发症

Title:Inflammatory Cells and Proteases in Abdominal Aortic Aneurysm and its Complications

Volume: 19 Issue: 11

关键词: 腹主动脉瘤，炎症细胞，蛋白酶，细胞外基质，巨噬细胞，动脉粥样硬化。

摘要: Abdominal aortic aneurysm (AAA), a common disease among elderly individuals, involves the progressive dilatation of the abdominal aorta as a consequence of degeneration. The mechanisms of AAA formation, development and rupture are largely unknown. Surgical repair is the only available method of treatment since the lack of knowledge regarding the pathogenesis of AAA has hindered the development of suitable medical treatments, particularly the development of drugs. In this review, we describe the inflammatory cells and proteases that may be involved in the formation and development of AAA. This knowledge can contribute to the development of new drugs for AAA.

Cite this article as:

Inflammatory Cells and Proteases in Abdominal Aortic Aneurysm and its Complications, Current Drug Targets 2018; 19 (11) . https://dx.doi.org/10.2174/1389450119666180531103458