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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

A Facile Procedure for Synthesis of Several 1, 4, 5-Trisubstituted-1Himidazole- 2(3H)-ones and -thiones via a One-pot Three-portion Reaction in Solvent and Microwave Irradiation

Author(s): Mohammad Shaker*

Volume 16, Issue 2, 2019

Page: [104 - 109] Pages: 6

DOI: 10.2174/1570178615666180522101532

Price: $65

Abstract

An ordinary procedure for the synthesis of several 1, 4, 5-trisubstituted-1H-imidazole- 2(3H)-ones and -thiones by a one-pot three-component reaction of glacial acetic acid under solvent, microwave irradiation condition is proposed. The products were formed through cyclization of benzoin with isothiocyanates or isocyanates and ammonium acetate. All incorporated combinations were determined for their spectral and microanalytical information. These compounds were subsequently studied for their fluorescence properties.

Keywords: Trisubstituted- 1H- imidazole- 2(3H)- ones and -thiones, multicomponent reactions, microwave irradiation, fluorescence, emission and absorption spectra, acetic acid.

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