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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

Biomedical Applications of Glycoconjugates

Author(s): Fei Ding and Yongmin Zhang*

Volume 18, Issue 18, 2018

Page: [1508 - 1523] Pages: 16

DOI: 10.2174/1389557518666180518083427

Price: $65

Abstract

Glycans expressed on the forefront surface of cells participate in many key biological processes via forming various glycoconjugates. The recognition of complex glycoconjugates as mediators of important biological processes has stimulated investigation into their therapeutic potential. As the increasing accessibility of glycoconjugates, it has been widely applied in the field of drug delivery. This review particularly refers to the constitutive glycoconjugates of receptor-mediated binding of glycoprotein, glycolipids and glycopeptides for cell-selective drug delivery, in order to broaden the future therapeutic scope of drug delivery system and effective cancer therapy.

Keywords: Drug delivery, glycoconjugates, glycolipid, glycopeptide, glycoprotein, targeting.

Graphical Abstract


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