Abstract
Safety and biocompatibility assessment of biomaterials are themes of constant concern as advanced materials enter the market as well as products manufactured by new techniques emerge. Within this context, this review provides an up-to-date approach on current methods for the characterization and safety assessment of biomaterials and biomedical devices from a physical-chemical to a biological perspective, including a description of the alternative methods in accordance with current and established international standards.
Keywords: Biomaterials, Physico-chemical characterization, Biocompatibility, In silico, In vitro, In vivo, Ex vivo, Alternative methods, International standards.
Graphical Abstract
Current Topics in Medicinal Chemistry
Title:Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards
Volume: 18 Issue: 4
Author(s): Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao
Affiliation:
- Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP, Sao Paulo – SP,Brazil
Keywords: Biomaterials, Physico-chemical characterization, Biocompatibility, In silico, In vitro, In vivo, Ex vivo, Alternative methods, International standards.
Abstract: Safety and biocompatibility assessment of biomaterials are themes of constant concern as advanced materials enter the market as well as products manufactured by new techniques emerge. Within this context, this review provides an up-to-date approach on current methods for the characterization and safety assessment of biomaterials and biomedical devices from a physical-chemical to a biological perspective, including a description of the alternative methods in accordance with current and established international standards.
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Oliveira P.R. Justine *, Melendez-Ortiz Ivan H. , Bucio Emilio, Alves Terra Patricia, Lima Ingrid Sousa Mayara , Goulart Ricardo Luiz , Mathor B. Monica , Varca H.C. Gustavo and Lugao B. Ademar , Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards, Current Topics in Medicinal Chemistry 2018; 18 (4) . https://dx.doi.org/10.2174/1568026618666180410151518
DOI https://dx.doi.org/10.2174/1568026618666180410151518 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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