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Review Article

偏头痛中的功能性神经影像生物标记：诊断，预后和治疗意义。

卷 26, 期 34, 2019

页: [6236 - 6252] 页: 17

弟呕挨: 10.2174/0929867325666180406115427

价格: $65

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摘要

背景：在当前的偏头痛临床实践中，通常寻求常规的神经影像学检查以排除继发性头痛或偏头痛相关疾病的可能原因。相反，尽管先进的磁共振成像（MRI）大大改善了我们对偏头痛患者的人脑过程的理解，但就目前的水平而言，他们还没有取代偏头痛临床环境中的常规神经成像技术。 方法：通过输入关键词“标志物”和/或“生物标志物”与“偏头痛”和/或“头痛”相结合，对PubMed引文进行全面审查。其他关键字包括“成像”或“神经成像”，“结构”或“功能”。唯一的限制是英语出版物。审查了所有符合这些条件的文章的摘要，并检索了全文并检查了相关文献。 结果：几位作者试图确定能够识别不同偏头痛表型的成像生物标志物，或者甚至更好地在疾病过程中对相同的偏头痛患者进行随访，以预测其演变为更严重的表型，以及最终对患者的反应。具体治疗。 结论：在偏头痛临床环境中识别诊断，预后和治疗性先进的神经影像生物标记物，以越来越合理和“量身定制”的方式接近患者，是非常有趣和未来的。不幸的是，偏头痛仍缺乏可靠而健壮的神经影像生物标记物，这可能是由于发病机理以及临床和神经影像异质性尚不完全清楚。虽然需要进行进一步的纵向高级神经影像学研究，以鉴定有效的神经影像生物标志物，但本综述旨在收集有关该主题的主要和最新著作。

关键词: 偏头痛，生物标志物，功能磁共振成像，诊断，预后，治疗。

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