摘要
基于证据的对现有文献的回顾最终建议在美国储存亚甲基蓝(MB)作为一种紧急解药。在日本,世界各地都有类似的报道,Gr。意大利和加拿大。由于观察到MB始终是紧急和危重护理单位所需的主要解药,因此需要重新审视其对NO/cGMP系统的影响,以重新强调。调整其多系统操作的大小。因此,本综述旨在展示MB在急诊室中的作用,涉及:1)多发性创伤和循环休克;2)神经保护;3)过敏反应;4)过量和中毒。
关键词: 亚甲基蓝,cGMP,一氧化氮,循环休克,神经保护,过敏,中毒。
图形摘要
Current Drug Targets
Title:Why Methylene Blue Have to Be Always Present in the Stocking of Emergency Antidotes
Volume: 19 Issue: 13
关键词: 亚甲基蓝,cGMP,一氧化氮,循环休克,神经保护,过敏,中毒。
摘要: Evidence-based review of the existing literature ultimately recommends stocking of Methylene Blue (MB) as an emergency antidote in the United States. The same is reported around the world in Japan, Greece, Italy and Canada. The observation that MB is always present as the main antidote required in emergency and critical care units calls for a revisit on its effects on the NO/cGMP system to reemphasize its multisystem actions. Therefore, the present review aimed to display the role of MB in emergency units, concerning: 1) Polytrauma and circulatory shock; 2) Neuroprotection, 3) Anaphylaxis and, 4) Overdose and poisoning.
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Cite this article as:
Why Methylene Blue Have to Be Always Present in the Stocking of Emergency Antidotes, Current Drug Targets 2018; 19 (13) . https://dx.doi.org/10.2174/1389450119666180403100410
DOI https://dx.doi.org/10.2174/1389450119666180403100410 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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