Synthesis of (2-iminomethyl)pyridine Moiety Supported on Hydroxyapatiteencapsulated-γ-Fe2O3 as an Inorganic-organic Hybrid Magnetic Nanocatalyst for the Synthesis of Thiazole Derivatives under Ultrasonic Irradiation

Title:Synthesis of (2-iminomethyl)pyridine Moiety Supported on Hydroxyapatiteencapsulated-γ-Fe2O3 as an Inorganic-organic Hybrid Magnetic Nanocatalyst for the Synthesis of Thiazole Derivatives under Ultrasonic Irradiation

Volume: 22 Issue: 13

Author(s): Mohammad Ahmadiazar and Manouchehr Mamaghani*

Affiliation:

• Department of Chemistry, Faculty of Sciences, University of Guilan, Rasht,Iran

Keywords: γ-Fe2O3@HAp, thiazole, rhodanine, thiazolone, ultrasonic irradiation, multicomponent reaction.

Abstract: A novel pyridine base modified core-shell (γ-Fe2O3@Hap (Hap: Hydroxyapatite)) inorganic-organic hybrid magnetic nanocatalyst has been introduced. The catalyst was fully characterized by spectroscopic analyses (FT-IR, FESEM, EDX, XRD) and its efficiency evaluated as a basic catalyst in one-pot multicomponent reaction of aryl aldehydes, rhodanine and piperidine under ultrasonic irradiation to obtain thiazole derivatives. This green, fast and straightforward protocol produced the products in short reaction times (14-40 min) and high to excellent yields (75-95%).

Cite this article as:

Ahmadiazar Mohammad and Mamaghani Manouchehr *, Synthesis of (2-iminomethyl)pyridine Moiety Supported on Hydroxyapatiteencapsulated-γ-Fe2O3 as an Inorganic-organic Hybrid Magnetic Nanocatalyst for the Synthesis of Thiazole Derivatives under Ultrasonic Irradiation, Current Organic Chemistry 2018; 22 (13) . https://dx.doi.org/10.2174/1385272822666180322121544