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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Review Article

Wittig- and Horner-Wadsworth-Emmons Olefination in Aqueous Media with and without Phase Transfer Catalysis

Author(s): Thies Thiemann*

Volume 15, Issue 5, 2018

Page: [412 - 432] Pages: 21

DOI: 10.2174/1570193X15666180221152118

Price: $65

Abstract

Wittig- and Horner-Wadsworth-Emmons (HWE) olefination remains a series of powerful reactions in the tool kit of organic synthesis. In the following article, an overview of the scope of Wittig and HWE olefination reactions in water or in multiphasic media under phase transfer conditions is presented. Special emphasis is given to one-pot, multi-component transformations. In the following article, the work on Wittig- and Horner-Wadsworth-Emmons reactions in aqueous media and under LL-PTC conditions is reviewed.

Keywords: Wittig reaction, Horner-Wadsworth-Emmons reaction, water, green chemistry, one-pot reaction, phase transfer.

Graphical Abstract


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