过敏致敏，抗组胺药，抗白三烯，哮喘，儿童期，皮质类固醇，人源化单克隆抗体，免疫治疗。

Title:Surface-bioengineered Gold Nanoparticles for Biomedical Applications

Volume: 25 Issue: 16

关键词: 金纳米粒子，生物功能化，生物分子，生物医学应用，生物工程，金纳米粒子。

摘要: The conjugation of gold nanoparticles (AuNPs) with biomolecules could create many outstanding biofunctions for the surface-functionalized nanoparticles and extend their biomedical applications. In this review, we summarize the recent advances in the surface bioengineering of AuNPs with biomolecules, such as DNA, proteins, peptides, and biopolymers, in which the details on the structure, functions, and properties of surface- bioengineered AuNPs are discussed. In addition, the surface-biofunctionalization of AuNPs for biomedical applications like biosensing, bioimaging, drug delivery, and tissue engineering are introduced. It is expected that this work will be very helpful for readers to understand the surface functionalization and engineering techniques for various metallic nanoparticles and design novel biomaterials for biomedical applications.

Cite this article as:

Surface-bioengineered Gold Nanoparticles for Biomedical Applications, Current Medicinal Chemistry 2018; 25 (16) . https://dx.doi.org/10.2174/0929867325666180117111404