摘要
O-异戊烯基香豆素(3,3-二甲基烯丙基,香叶基 - ,法呢基和相关的生物合成衍生物)代表一类很少发生的天然产物。 在过去的二十年中,已经发现这种次级代谢物具有有希望的和有效的药理学性质,主要是在抗癌和抗炎特性方面。 迄今为止,已经从植物,真菌和细菌中提取了大约160个羟苯丙酮香豆素。 柑橘属已被证明是最丰富的标题产品之一。 这篇全面综述的目的是对迄今为止报道的关于从植物化学和药理学观点来看在该属中发现的主要O-异戊烯基香豆素的文献引用进行调查,并且迄今未报道的文献中没有对其进行调查 制作。
关键词: 柑橘属。 香豆素,呋喃香豆素,氧化烯丙基化次级代谢物,苯丙素,芸香科,真菌,细菌。
Current Medicinal Chemistry
Title:Prenylated Coumarins of the Genus Citrus: An Overview of the 2006- 2016 Literature Data
Volume: 25 Issue: 10
关键词: 柑橘属。 香豆素,呋喃香豆素,氧化烯丙基化次级代谢物,苯丙素,芸香科,真菌,细菌。
摘要: O-Prenyl coumarins (3,3-dimethylallyl, geranyl-, farnesyl- and related biosynthetic derivatives) represent a class of rarely occurring natural products. In the last two decades, such secondary metabolites have been found to possess promising and effective pharmacological properties, mainly in terms of anti-cancer and anti-inflammatory properties. To date, about 160 oxyprenylated coumarins have been extracted from plants, fungi, and bacteria. The genus Citrus has been demonstrated to be among the richest source of the title products. The aim of this comprehensive review is to make a survey of the so far reported literature citations about the main O-prenyl coumarins found in this genus from phytochemical and pharmacological point of views and for which no surveys of the in so far reported literature have been made.
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Cite this article as:
Prenylated Coumarins of the Genus Citrus: An Overview of the 2006- 2016 Literature Data, Current Medicinal Chemistry 2018; 25 (10) . https://dx.doi.org/10.2174/0929867325666180104154443
DOI https://dx.doi.org/10.2174/0929867325666180104154443 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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