Abstract
The coupling reaction of terminal alkynes and CO2 provides a promising way to synthesize propiolic acids. Among the existing catalytic systems, transition-metal copper and silver exhibit excellent catalytic efficiency under mild conditions probably being attributed to the activation of C-C triple bond of terminal alkynes. In this aspect, efficient strategies for activating both substrate and CO2 are often smart choices. This review summarizes the development trend of the Cu/Ag-catalyzed carboxylation reactions of terminal alkynes with CO2, and representative examples are also discussed in detail.
Keywords: Carbon dioxide, carboxylation, terminal alkyne, propiolic acids, transition metal, catalysis.
Graphical Abstract
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
64
9