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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Thrombolytic Therapy in the Current ERA: Myocardial Infarction and Beyond

Author(s): Patrick Proctor, Massoud A. Leesar and Arka Chatterjee*

Volume 24, Issue 4, 2018

Page: [414 - 426] Pages: 13

DOI: 10.2174/1381612824666171227211623

Price: $65

Abstract

Thrombolytic therapy kick-started the era of modern cardiology but in the last few decades it has been largely supplanted by primary percutaneous coronary intervention (PCI) as the go-to treatment for acute myocardial infarction. However, these agents remain important for vast populations without access to primary PCI and acute ischemic stroke. More innovative uses have recently come up for the treatment of a variety of conditions. This article summarizes the history, evidence base and current use of thrombolytics in cardiovascular disease.

Keywords: Thrombolysis, acute myocardial infarction, catheter directed thrombolysis, pulmonary embolism, acute ischemic stroke, thrombolytic therapy.


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