Purification Strategies for Combinatorial and Parallel Chemistry

Title: Purification Strategies for Combinatorial and Parallel Chemistry

Volume: 6 Issue: 1

Author(s): Paul J. Edwards

Affiliation:

Keywords: fluorous synthesis, combinatorial chemistry, parallel chemistry, puriffication strategy, liquid-phase combinatorial chemistry

Abstract: This review surveys the methods developed for the purification of intermediates and final compounds originating from parallel and combinatorial chemistry. Included will be reviews of polymerassisted purification, liquid-phase combinatorial chemistry, fluorous synthesis, liquid-liquid and solid-phase extraction, reverse-phase HPLC and supercritical fluid chromatography. A critique of each method is given, highlighting the methodologies strengths and weaknesses.

Cite this article as:

Edwards J. Paul, Purification Strategies for Combinatorial and Parallel Chemistry, Combinatorial Chemistry & High Throughput Screening 2003; 6 (1) . https://dx.doi.org/10.2174/1386207033329832

DOI https://dx.doi.org/10.2174/1386207033329832	Print ISSN 1386-2073
Publisher Name Bentham Science Publisher	Online ISSN 1875-5402