[1]
Li, Y.; Shi, S.; Gao, J.; Han, S.; Wu, X.; Jia, Y.; Su, L.; Shi, J.; Hu, D. Cryptotanshinone downregulates the profibrotic activities of hypertrophic scar fibroblasts and accelerates wound healing: A potential therapy for the reduction of skin scarring. Biomed. Pharmacother., 2016, 80, 80-86.
[2]
Shang, Q.; Xu, H.; Huang, L. Tanshinone IIA: A promising natural cardioprotective agent. Evid. Based Complement. Alternat. Med., 2012, 2012, 716459.
[3]
Zhou, L.; Zuo, Z.; Chow, M.S. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J. Clin. Pharmacol., 2005, 45(12), 1345-1359.
[4]
Xie, Z.; Loi Truong, T.; Zhang, P.; Xu, F.; Xu, X.; Li, P. Dan-Qi prescription ameliorates insulin resistance through overall corrective regulation of glucose and fat metabolism. J. Ethnopharmacol., 2015, 172, 70-79.
[5]
Gao, L.N.; Yan, K.; Cui, Y.L.; Fan, G.W.; Wang, Y.F. Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury. World J. Gastroenterol., 2015, 21(30), 9079-9092.
[6]
Jian, W.; Yu, S.; Tang, M.; Duan, H.; Huang, J. A combination of the main constituents of Fufang Xueshuantong Capsules shows protective effects against streptozotocin-induced retinal lesions in rats. J. Ethnopharmacol., 2016, 182, 50-56.
[7]
Guo, X.J.; Jiang, Z.; Zhao, P.F.; Fang, L.L.; Hu, X.Y.; Wang, P.; Guo, X. Pharmacokinetic study of four components in rat plasma after oral administration of Guanmaitong Granule by UPLC-MS/MS. Curr. Pharm. Anal., 2018, 14(3), 223-232.
[8]
Si, Y.; Li, N.; Tong, L.; Lin, B.; Wang, W.; Xing, Y.; Liu, X.; Yue, H.; Xu, J.; Ju, A. Bioactive minor components of the total salvianolic acids injection prepared from Salvia miltiorrhiza Bge. Bioorg. Med. Chem. Lett., 2016, 26(1), 82-86.
[9]
Ren-an, Q.; Juan, L.; Chuyuan, L.; Wenjuan, F.; Chunyan, H.; Xuemei, Y.; Lin, H.; Hong, N. Study of the protective mechanisms of Compound Danshen Tablet (Fufang Danshen Pian) against myocardial ischemia/reperfusion injury via the Akt-eNOS signaling pathway in rats. J. Ethnopharmacol., 2014, 156, 190-198.
[10]
Hu, P.; Liang, Q.L.; Luo, G.A.; Zhao, Z.Z.; Jiang, Z.H. Multi-component HPLC fingerprinting of Radix Salviae Miltiorrhizae and its LC-MS-MS identification. Chem. Pharm. Bull. (Tokyo), 2005, 53(6), 677-683.
[11]
Liu, M.; Li, Y.G.; Zhang, F.; Yang, L.; Chou, G.X.; Wang, Z.T.; Hu, Z.B. Chromatographic fingerprinting analysis of Danshen root (Salvia miltiorrhiza Radix et Rhizoma) and its preparations using high performance liquid chromatography with diode array detection and electrospray mass spectrometry (HPLC-DAD-ESI/MS). J. Sep. Sci., 2007, 30(14), 2256-2267.
[12]
Huang, J.; Qin, Y.; Liu, B.; Li, G.Y.; Ouyang, L.; Wang, J.H. In silico analysis and experimental validation of molecular mechanisms of salvianolic acid A-inhibited LPS-stimulated inflammation, in RAW264.7 macrophages. Cell Prolif., 2013, 46(5), 595-605.
[13]
Fan, H.Y.; Fu, F.H.; Yang, M.Y.; Xu, H.; Zhang, A.H.; Liu, K. Antiplatelet and antithrombotic activities of salvianolic acid A. Thromb. Res., 2010, 126(1), e17-e22.
[14]
Xu, X.; Hu, Y.; Zhai, X.; Lin, M.; Chen, Z.; Tian, X.; Zhang, F.; Gao, D.; Ma, X.; Lv, L.; Yao, J. Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice. Toxicol. Appl. Pharmacol., 2013, 273(1), 68-76.
[15]
Wu, Z.M.; Wen, T.; Tan, Y.F.; Liu, Y.; Ren, F.; Wu, H. Effects of salvianolic acid a on oxidative stress and liver injury induced by carbon tetrachloride in rats. Basic Clin. Pharmacol. Toxicol., 2007, 100(2), 115-120.
[16]
Wang, S.B.; Tian, S.; Yang, F.; Yang, H.G.; Yang, X.Y.; Du, G.H. Cardioprotective effect of salvianolic acid A on isoproterenol-induced myocardial infarction in rats. Eur. J. Pharmacol., 2009, 615(1-3), 125-132.
[17]
Xu, T.; Wu, X.; Chen, Q.; Zhu, S.; Liu, Y.; Pan, D.; Chen, X.; Li, D. The anti-apoptotic and cardioprotective effects of salvianolic acid a on rat cardiomyocytes following ischemia/reperfusion by DUSP-mediated regulation of the ERK1/2/JNK pathway. PLoS One, 2014, 9(7), e102292.
[18]
Qiang, G.; Yang, X.; Shi, L.; Zhang, H.; Chen, B.; Zhao, Y.; Zu, M.; Zhou, D.; Guo, J.; Yang, H.; Zhang, L.; Du, G. Antidiabetic effect of salvianolic acid a on diabetic animal models via AMPK activation and mitochondrial regulation. Cell. Physiol. Biochem., 2015, 36(1), 395-408.
[19]
Wu, P.; Yan, Y.; Ma, L.L.; Hou, B.Y.; He, Y.Y.; Zhang, L.; Niu, Z.R.; Song, J.K.; Pang, X.C.; Yang, X.Y.; Du, G.H. Effects of the nrf2 protein modulator salvianolic acid A alone or combined with metformin on diabetes-associated macrovascular and renal injury. J. Biol. Chem., 2016, 291(42), 22288-22301.
[20]
Yu, X.; Zhang, L.; Yang, X.; Huang, H.; Huang, Z.; Shi, L.; Zhang, H.; Du, G. Salvianolic acid A protects the peripheral nerve function in diabetic rats through regulation of the AMPK-PGC1alpha-Sirt3 axis. Molecules, 2012, 17(9), 11216-11228.
[21]
Yang, X.Y.; Qiang, G.F.; Zhang, L.; Zhu, X.M.; Wang, S.B.; Sun, L.; Yang, H.G.; Du, G.H. Salvianolic acid A protects against vascular endothelial dysfunction in high-fat diet fed and streptozotocin-induced diabetic rats. J. Asian Nat. Prod. Res., 2011, 13(10), 884-894.
[22]
Yang, X.Y.; Sun, L.; Xu, P.; Gong, L.L.; Qiang, G.F.; Zhang, L.; Du, G.H. Effects of salvianolic scid A on plantar microcirculation and peripheral nerve function in diabetic rats. Eur. J. Pharmacol., 2011, 665(1-3), 40-46.
[23]
Sun, J.; Zhang, L.; Song, J.; Tian, S.; Huang, C.; Feng, Z.; Lv, Y.; Du, G. Pharmacokinetic study of salvianolic acid A in beagle dog after oral administration by a liquid chromatography-mass spectrometry method: a study on bioavailability and dose proportionality. J. Ethnopharmacol., 2013, 148(2), 617-623.
[24]
Hou, Y.Y.; Peng, J.M.; Chao, R.B. Pharmacokinetic study of salvianolic acid A in rat after intravenous administration of Danshen injection. Biomed. Chromatogr., 2007, 21(6), 598-601.
[25]
Zhang, X.R.; Pan, W.S. Quantitative determination of salvianolic acid A in rat plasma by HPLC. Chinese Traditional and Herbal Drugs, 2002, 33(5), 410-412.
[26]
Zhao, D.; Han, D.E.; Li, N.; Lu, Y.; Li, T.T.; Yang, S.Y.; He, J.K.; Chen, X.J. Simultaneous determination of six phenolic constituents of Danshen injection in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study. Eur. J. Mass Spectrom. (Chichester), 2011, 17(4), 395-403.
[27]
Chang, B.B.; Zhang, L.; Cao, W.W.; Cao, Y.; Yang, W.L.; Wang, Y.; Chen, Y.C.; Liu, X.Q. Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats. Acta Pharmacol. Sin., 2010, 31(5), 638-646.
[28]
Li, X.; Du, F.; Jia, W.; Olaleye, O.E.; Xu, F.; Wang, F.; Li, L. Simultaneous determination of eight Danshen polyphenols in rat plasma and its application to a comparative pharmacokinetic study of DanHong injection and Danshen injection. J. Sep. Sci., 2017, 40(7), 1470-1481.
[29]
Pei, L.; Bao, Y.; Wang, H.; Yang, F.; Xu, B.; Wang, S.; Yang, X.; Du, G. A sensitive method for determination of salvianolic acid A in rat plasma using liquid chromatography/tandem mass spectrometry. Biomed. Chromatogr., 2008, 22(7), 786-794.
[30]
Wang, H.; Li, X.; Zhang, W.; Liu, Y.; Wang, S.; Liu, X.; He, H. Mechanism-based pharmacokinetic-pharmacodynamic modeling of salvianolic acid A effects on plasma xanthine oxidase activity and uric acid levels in acute myocardial infarction rats. Xenobiotica, 2017, 47(3), 208-216.
[31]
Wang, S.P.; Liu, L.; Wang, L.L.; Jiang, P.; Xiang, L.; Zhang, W.D.; Liu, R.H. Simultaneous determination of six hydrophilic components in rat plasma after oral administration of Jitai tablet by liquid chromatography-electrospray ionization-tandem mass spectrometry: application to a pharmacokinetic study. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2013, 912, 75-84.
[32]
Du, , G.H.; Zhang, W.K; Zhang, L.. ; Zhao, Y.; Wang, S.B.; Yang, H.G.; Tian, S A method of preparation of salvianolic acid A CN102731308A (in Chinese)., 2012.
[33]
Han, D.E.; Zheng, Y.; Chen, X.; He, J.; Zhao, D.; Yang, S.; Zhang, C.; Yang, Z. Identification and characterization of human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of salvianolic acid A. Drug Metab. Pharmacokinet., 2012, 27(6), 579-585.
[34]
Xu, J.; Zeng, S.; Chen, X.; Qu, H. Isolation and identification of degradation products of salvianolic acid A by NMR and LC-MS. Fitoterapia, 2011, 82(2), 260-266.
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