New Insights into Adipokines as Potential Biomarkers for Type-2 Diabetes Mellitus

doi:10.2174/0929867325666171205162248
摘要

大量研究集中在研究与2型糖尿病风险或诊断相关的血清生物标志物上。在过去的十年中，有前途的研究表明，循环水平的脂肪因子可以用作糖尿病进展以及未来治疗目标的相关生物标志物。在这里，我们讨论了可能的使用最近描述的脂肪因子，包括apelin，omentin-1，resistin，FGF-21，neuregulin-4和visfatin作为糖尿病的早期生物标记。此外，我们还包括其他众所周知的脂肪因子（如瘦素和脂联素）的最新发现。总之，需要进一步的研究来阐明这些生物学因素作为2型糖尿病及其相关功能障碍的潜在生物标志物的病理生理学意义和临床价值。
关键词: 脂肪因子，糖尿病，2型糖尿病，胰岛素抵抗，肥胖症，葡萄糖代谢。
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DOI https://dx.doi.org/10.2174/0929867325666171205162248	Print ISSN 0929-8673
Publisher Name Bentham Science Publisher	Online ISSN 1875-533X
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