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Review Article

荧光素启发的近红外化学计量仪用于发光生物成像。

卷 26, 期 21, 2019

页: [4029 - 4041] 页: 13

弟呕挨: 10.2174/0929867324666171024101715

价格: $65

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摘要

发光生物成像技术广泛用于实时，高时空分辨率地对生物目标进行无创监测。为了在体内进行有效的生物成像，开发智能有机染料平台至关重要。荧光素（FL）是一种传统染料，已广泛用于生物学和临床研究。然而，可见的激发和发射限制了它们在体内生物成像中的进一步应用。近红外（NIR）染料显示出生物成像的优势，因为它们对生物样品的吸收和光损伤最小，并且组织的穿透力很强，并且自活体背景产生的自发光低。因此，近红外荧光素启发的染料的一些重大发展已经出现，可以用于体外和体内生物应用。在这篇综述中，我们重点介绍了基于荧光素激发的染料萘荧光素（NPF）和花菁荧光素（Cy-FL）的修饰，用于检测和生物成像的近红外化学计量仪的开发进展。

关键词: 近红外，萘-荧光素，花青-荧光素，发光，化学计量仪，生物成像。

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