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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Recent Advances in the Synthesis of 1,3-Diketones

Author(s): Alexander V. Kel'in

Volume 7, Issue 16, 2003

Page: [1691 - 1711] Pages: 21

DOI: 10.2174/1385272033486233

Price: $65

Abstract

The most recent achievements in the construction of the 1,3-diketone moiety are reviewed. Though both classical and modern approaches to the synthesis of 1,3-diketones are compared and analyzed in terms of efficiency, functional group compatibility, regio-, and stereoselectivity, main attention is paid to recently discovered methods based on rearrangements and concerted mechanisms. Molecular structure investigations, appearance in nature, and biological activity of 1,3-diketones are also briefly reviewed.

Keywords: Synthesis of 1,3-Diketones, 1,3-diketone moiety, stereoselectivity, biological activity

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