生物医用水凝胶的结构设计及理化基础

Title:Structural Design and Physicochemical Foundations of Hydrogels for Biomedical Applications

Volume: 25 Issue: 8

关键词: 水凝胶，组织工程，药物传递，免疫疗法，疫苗，生物医学应用。

摘要: Biomedical research, known as medical research, is conducive to support and promote the development of knowledge in the field of medicine. Hydrogels have been extensively used in many biomedical fields due to their highly absorbent and flexible properties. The smart hydrogels, especially, can respond to a broad range of external stimuli such as temperature, pH value, light, electric and magnetic fields. With excellent biocompatibility, tunable rheology, mechanical properties, porosity, and hydrated molecular structure, hydrogels are considered as promising candidate for simulating local tissue microenvironment. In this review article, we mainly focused on the most recent development of engineering synthetic hydrogels; moreover, the classification, properties, especially the biomedical applications including tissue engineering and cell scaffolding, drug and gene delivery, immunotherapies and vaccines, are summarized and discussed.

Cite this article as:

Structural Design and Physicochemical Foundations of Hydrogels for Biomedical Applications, Current Medicinal Chemistry 2018; 25 (8) . https://dx.doi.org/10.2174/0929867324666170818111630