Synthesis of 2,4,5-Triaryl-1H-Imidazoles under Kornblum Oxidative Condition

Mohammad    Hosein     Sayahi; Mina        Bahmei; Setareh        Moghimi; Mohammad        Mahdavi; Loghman        Firoozpour; Alireza        Foroumadi

doi:10.2174/1570178614666170726125544

Abstract

2,4,5-Triaryl-1H-imidazoles were synthesized from benzyl bromides under Kornblum oxidative condition. The reaction proceeded via an in situ oxidation followed by condensation to afford the desired products in good yields.

Keywords: Imidazoles, Kornblum oxidation, benzyl halide, one-pot, three-component reaction, MCRs.

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Letters in Organic Chemistry

Title:Synthesis of 2,4,5-Triaryl-1H-Imidazoles under Kornblum Oxidative Condition

Volume: 15 Issue: 6

Author(s): Mohammad Hosein Sayahi, Mina Bahmei, Setareh Moghimi, Mohammad Mahdavi, Loghman Firoozpour and Alireza Foroumadi*

Affiliation:

Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran,Iran

Keywords: Imidazoles, Kornblum oxidation, benzyl halide, one-pot, three-component reaction, MCRs.

Abstract: 2,4,5-Triaryl-1H-imidazoles were synthesized from benzyl bromides under Kornblum oxidative condition. The reaction proceeded via an in situ oxidation followed by condensation to afford the desired products in good yields.

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Sayahi Hosein Mohammad , Bahmei Mina , Moghimi Setareh , Mahdavi Mohammad , Firoozpour Loghman and Foroumadi Alireza *, Synthesis of 2,4,5-Triaryl-1H-Imidazoles under Kornblum Oxidative Condition, Letters in Organic Chemistry 2018; 15 (6) . https://dx.doi.org/10.2174/1570178614666170726125544

DOI https://dx.doi.org/10.2174/1570178614666170726125544	Print ISSN 1570-1786
Publisher Name Bentham Science Publisher	Online ISSN 1875-6255