Solvent-Free Synthesis of Thiobarbituric Acids Using Amberlyst-15 as a Green Catalyst

Title:Solvent-Free Synthesis of Thiobarbituric Acids Using Amberlyst-15 as a Green Catalyst

Volume: 4 Issue: 1

Author(s): Manish M. Katiya, Madhukar G. Dhonde*Jayant M. Gajbhiye

Affiliation:

• Department of Chemistry, Shri Mathuradas Mohota College of Science, Nagpur – 440009,India

Keywords: Thioureas, malonyl chloride, thiobarbituric acid, recyclability, amberlyst-15, plausible mechanism.

Abstract: Background: Solvent-free reaction for the synthesis of thiobarbituric acids (TBAs) by the reaction of 1,3-disubstituted thioureas and malonyl chloride using Amberlyst-15 as a green catalyst has been reported. Recyclability of the catalyst was possible up to five runs without loss of catalytic activity.

Conclusion: The simple workup, isolation without column, excellent yields, is main advantages of present protocol.

Cite this article as:

Katiya M. Manish , Dhonde G. Madhukar *, Gajbhiye M. Jayant , Solvent-Free Synthesis of Thiobarbituric Acids Using Amberlyst-15 as a Green Catalyst, Current Green Chemistry 2017; 4 (1) . https://dx.doi.org/10.2174/2213346104666170704115006

DOI https://dx.doi.org/10.2174/2213346104666170704115006	Print ISSN 2213-3461
Publisher Name Bentham Science Publisher	Online ISSN 2213-347X