Natural and Synthetic Xanthonolignoids: Chemistry and Biological Activities

M.   M.M.   Pinto; E.   P.   Sousa

doi:10.2174/0929867033368574

Abstract

Natural xanthonolignoids are formed by the coupling of cinnamyl alcohol with an appropriate ortho-dihydroxyxanthone. More than twenty xanthonolignoids have been isolated and synthesized and some interesting pharmacological activities of these compounds have been described. The purpose of this review is to describe the natural occurrence, isolation, structure elucidation and synthesis - both biomimetic and classic -as well as biological activities of xanthonolignoids. Aspects related to biosynthesis will also be considered.

Keywords: Xanthonolignoids, cinnamyl alcohol, ortho-dihydroxyxanthone

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Current Medicinal Chemistry

Title: Natural and Synthetic Xanthonolignoids: Chemistry and Biological Activities

Volume: 10 Issue: 1

Author(s): M. M.M. Pinto and E. P. Sousa

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Keywords: Xanthonolignoids, cinnamyl alcohol, ortho-dihydroxyxanthone

Abstract: Natural xanthonolignoids are formed by the coupling of cinnamyl alcohol with an appropriate ortho-dihydroxyxanthone. More than twenty xanthonolignoids have been isolated and synthesized and some interesting pharmacological activities of these compounds have been described. The purpose of this review is to describe the natural occurrence, isolation, structure elucidation and synthesis - both biomimetic and classic -as well as biological activities of xanthonolignoids. Aspects related to biosynthesis will also be considered.

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Pinto M.M. M. and Sousa P. E., Natural and Synthetic Xanthonolignoids: Chemistry and Biological Activities, Current Medicinal Chemistry 2003; 10 (1) . https://dx.doi.org/10.2174/0929867033368574