Abstract
Our ability to study thousands of genes simultaneously over the last few years owing not only to the development of DNA microarray technology, but also to large-scale yeast two-hybrid and other methods, has brought about a paradigmatic shift in biology. Armed with the complete sequences of several genomes including humans, more and more biomedical investigators are now interested in understanding the functions of gene products, or proteins, on a global scale. In this article, the promises and pitfalls of two methods used for proteomics studies - protein microarrays and mass spectrometry - towards achieving this goal are discussed.
Keywords: paradigmatic, protein microarrays, spectrometry, genomes, Proteomics
Current Genomics
Title: Microarrays and Mass Spectrometry - The Future of Proteomics
Volume: 4 Issue: 7
Author(s): K. S. Deshpande, H. C. Harsha and A. Pandey
Affiliation:
Keywords: paradigmatic, protein microarrays, spectrometry, genomes, Proteomics
Abstract: Our ability to study thousands of genes simultaneously over the last few years owing not only to the development of DNA microarray technology, but also to large-scale yeast two-hybrid and other methods, has brought about a paradigmatic shift in biology. Armed with the complete sequences of several genomes including humans, more and more biomedical investigators are now interested in understanding the functions of gene products, or proteins, on a global scale. In this article, the promises and pitfalls of two methods used for proteomics studies - protein microarrays and mass spectrometry - towards achieving this goal are discussed.
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Cite this article as:
Deshpande S. K., Harsha C. H. and Pandey A., Microarrays and Mass Spectrometry - The Future of Proteomics, Current Genomics 2003; 4 (7) . https://dx.doi.org/10.2174/1389202033490213
DOI https://dx.doi.org/10.2174/1389202033490213 |
Print ISSN 1389-2029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5488 |
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