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Review Article

糖尿病对心脏和血管疾病的影响：钙信号的作用

卷 26, 期 22, 2019

页: [4166 - 4177] 页: 12

弟呕挨: 10.2174/0929867324666170523140925

价格: $65

摘要

糖尿病和心血管疾病（CVD）的病理生理学是复杂和多因素的。 与糖尿病相关的心肌病的特定类型，称为糖尿病性心肌病（DCM），被认为是在没有冠状动脉粥样硬化和高血压的情况下，糖尿病患者心脏结构和功能重塑的无症状进展。 换句话说，特别是在糖尿病患者中存在心脏病也被称为糖尿病心脏病。 本文回顾了糖尿病对心脏和血管床的影响，重点研究了涉及氧化应激，炎症，内皮功能障碍和钙稳态变化的分子机制，以及其他机制。 了解这些机制将有助于识别和治疗糖尿病患者的CVD，并计划有效的策略来减轻DCM对这些患者的影响。

关键词: 心血管疾病，糖尿病，糖尿病性心肌病，钙稳态，氧化应激，内皮功能障碍。

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