The Possible Hypoglycemic Mechanisms of Echinochrome

Title:The Possible Hypoglycemic Mechanisms of Echinochrome

Volume: 14 Issue: 4

Author(s): Ayman Saber Mohamed*, Amel Mahmoud Soliman and Mohamed-Assem Said Marie

Affiliation:

• Zoology Department, Faculty of Science, Cairo University, 12613, Giza,Egypt

Keywords: Echinochrome, diabetes, acetylcholine, insulin resistance, oxidative stress, hypoglycemic mechanisms.

Abstract: Background: Diabetes mellitus is the main reason of morbidity and mortality worldwide. In recent years great attention has been paid to bioactivity of natural products due to their potential pharmacological utilization. Echinochrome is a natural compound isolated from sea urchins and possesses many biological effects. The hypoglycemic activity of echinochrome reported in many recent experiments.

Objective: In our study, we tried to collect all the possible hypoglycemic mechanism of echinochrome.

Conclusion: The hypoglycemic effect of echinochrome involving four main pathways; regeneration of pancreas, decrease insulin resistant, increase insulin production and improve glucose homeostasis.

Cite this article as:

Mohamed Saber Ayman *, Soliman Mahmoud Amel and Marie Said Mohamed-Assem , The Possible Hypoglycemic Mechanisms of Echinochrome, Current Diabetes Reviews 2018; 14 (4) . https://dx.doi.org/10.2174/1573399813666170505120119